Compare Videx vs. Retrovir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Videx
(didanosine or ddl)

Retrovir
(zidovudine, azt, or zdv)

Works with other medicines to treat HIV infection. Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, Videx can be a difficult drug to take. Videx has numerous serious side effects. It is also difficult taking Videx twice a day on an empty stomach.Works with other medicines to treat HIV infection. Also prevents mother-to-child sharing of HIV. AZT can be a good second-line choice to take within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class. AZT can have a number of serious side effects, but if you don't have prior blood, kidney, or liver problems, you should consider it.
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Videx (didanosine or ddl)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Retrovir (zidovudine, azt, or zdv)?
Worth itNot sureNot worth it
Side effects
VidexRetrovir

We haven’t found good data for Videx side effects.

FDA side effect reports for Videx »

We haven’t found good data for Retrovir side effects.

FDA side effect reports for Retrovir »
How it works
VidexRetrovir
Videx stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.AZT stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.
Type of medication
VidexRetrovir
Prescription only
Available as
VidexRetrovir
  • Extended release
  • Liquid
  • Pill
  • Pill
  • Liquid
Used for
VidexRetrovir
  • HIV Infection
  • HIV Infection
Risk factors for serious side effects
VidexRetrovir
  • Kidney problems
  • Use of stavudine, another HIV drug
  • Women
  • Use of hydroxyurea, stavudine, and Videx together
Detailed Videx (didanosine or ddl) risks & warnings »
  • Advanced HIV
  • Anemia
  • Neutropenia
  • Longtime use of AZT
  • Women
Detailed Retrovir (zidovudine, azt, or zdv) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
VidexRetrovir
No food related info.
  • Take AZT with or without food.
Kidneys and liver
VidexRetrovir
  • Videx can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use Videx. It may not be a good choice for people with liver problems.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • AZT can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use AZT. It may not be a good choice for people with liver problems.
  • Poor kidney function will affect how much AZT you can take.
Pain
VidexRetrovir
No pain related info.
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis), and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
Upsides and benefits
VidexRetrovir
  • The oral solution can be stored in the refrigerator for up to 30 days.
  • While Videx doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
  • AZT is provided as capsules, tablets, and syrup.
  • Used in kids and babies.
  • Take AZT with or without food.
  • AZT is included in the combination drugs Trizivir (AZT, Epivir, and Ziagen) and Combivir (AZT and Epivir), both of which are taken twice a day.
Downsides and risks
VidexRetrovir
  • Must take on an empty stomach at least 30 minutes before, or 2 hours after eating.
  • Take twice a day.
  • The amount of Videx you will take is based on your body weight, kidney, and liver function.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
  • AZT may cause serious blood, muscle, and liver problems.
  • Poor kidney function will affect how much AZT you can take.
  • Allergies to AZT are rare, but very serious.
  • Need to get regular blood tests.
Tips from our pharmacists for people taking the medication
VidexRetrovir
  • Talk with your doctor about all other medications you are taking since Videx interacts with many other drugs.
  • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking Videx and report them to your doctor.
  • Read the Medication Guide given to you at the pharmacy about Videx since it contains helpful information.
  • Don't take AZT with stavudine, another HIV drug.
  • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking AZT and report them to your doctor.
  • Read the Medication Guide given to you at the pharmacy about AZT since it contains helpful information.
Learn more
More about VidexSide effectsAlternativesFDA package insert
Have you used Videx (didanosine or ddl)?
Worth itNot sureNot worth it
More about RetrovirSide effectsAlternativesFDA package insert
Have you used Retrovir (zidovudine, azt, or zdv)?
Worth itNot sureNot worth it