Compare Viread vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Viread
(tenofovir)

Zerit
(stavudine)

Works with other medicines to treat HIV infection. Also treats Hepatitis B Virus. Viread (tenofovir) is a first-line choice to be used in combination with other medications to treat HIV. Viread (tenofovir) is also a first-line choice in treating HBV.Works with other medicines to treat HIV infection. Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.
Reviews & ratings
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Have you used Viread (tenofovir)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Zerit (stavudine)?
Worth itNot sureNot worth it
Side effects
VireadZerit
  • Rash 18%
  • Diarrhea 5%
  • Headache 14%
  • Pain 13%
  • Low mood disorder 11%
  • Nausea 4%
  • Weakness 10%
  • Back pain 9%
  • Abdominal pain 22%
  • Sleep difficulty 18%
More Viread side effects »

We haven’t found good data for Zerit side effects.

FDA side effect reports for Zerit »
How it works
VireadZerit
Viread (tenofovir) is a nucleoside reverse transcriptase inhibitor that prevents both HIV and hepatitis B virus from making copies of itself.stavudine stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.
Type of medication
VireadZerit
Available as
VireadZerit
  • Pill
  • Powder
  • Pill
  • Liquid
Used for
VireadZerit
  • HIV Infection
Risk factors for serious side effects
VireadZerit
  • Liver disease
  • Women
  • Obesity
  • Hepatitis B Virus infection
  • History of mental illness
Detailed Viread (tenofovir) risks & warnings »
  • Use of hydroxyurea, didanosine, and stavudine together
  • HIV
  • Exposure to other infections
  • Start of a new HIV medication
  • Change in HIV therapy
Detailed Zerit (stavudine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
VireadZerit
No interactions related info.
  • Interacts with many different medications.
Food
VireadZerit
  • Taken only once daily, with or without food.
  • Take with or without food.
Kidneys and liver
VireadZerit
  • Viread (tenofovir) is not yet approved for treating Hepatitis B. If you have hepatitis B and HIV, don't stop taking Viread (tenofovir) without talking to your doctor since your hepatitis can get worse. Your doctor will check your liver regularly.
  • People on Viread (tenofovir) have reported kidney damage, which can be made worse if you take high doses of anti-inflammatory drugs called NSAIDs (Motrin/Advil, Aleve, Mobic, Voltaren, etc.). Call your doctor if you develop bone pain, pain in your arms or legs, or pain and weakness in your muscles.
  • There are newer formulations of Viread (tenofovir) available that are safer on your kidneys.
  • Not recommended for patients with kidney damage.
  • stavudine can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use stavudine. It may not be a good choice for people with liver problems.
  • May cause serious side effects in your liver, kidneys, and pancreas.
Upsides and benefits
VireadZerit
  • Can be used with other medications to prevent HIV infection after an exposure.
  • Taken only once daily, with or without food.
  • There are newer formulations of Viread (tenofovir) available that are safer on your kidneys.
  • If tablets are hard for you to swallow, Viread (tenofovir) is available in a powder that's mixed with soft foods.
  • stavudine is provided as both capsules and an oral solution.
  • Take with or without food.
  • Can be used by patients on dialysis.
  • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides and risks
VireadZerit
  • Viread (tenofovir) can't be used on its own to treat HIV infection.
  • Not recommended for patients with kidney damage.
  • Can weaken your bones.
  • Might worsen hepatitis B infections if you suddenly stop taking it.
  • Must take twice a day, every 12 hours.
  • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
  • Interacts with many different medications.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
Tips from our pharmacists for people taking the medication
VireadZerit
  • Avoid taking NSAIDs (non-steroidal anti-inflammatory drugs) like aspirin, ibuprofen, and Aleve in order to prevent damage to kidneys.
  • Patients should be tested for both HIV and Hepatitis B virus (HBV) before starting Viread (tenofovir).
  • Viread (tenofovir) powder should be mixed into soft food like applesauce or yogurt. Take it immediatly after mixing, otherwise the taste can turn bitter. Viread (tenofovir) powder cannot be mixed into liquids.
  • Immediately report any signs of liver problems (jaundice, dark urine, yellowing of eyes, etc.) or sensitivity reactions (rash, fever, fatigue, difficulty breathing, etc.) to your prescriber.
  • Keep your regularly scheduled doctor's and lab appointments. These help ensure your medication is working well and safely.
  • Set a timer on your phone to make sure you don't forget to take stavudine at the right time.
  • Talk with your doctor about all other medications you are taking since stavudine interacts with many other drugs.
  • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking stavudine and report them to your doctor.
Learn more
More about VireadSide effectsAlternativesFDA package insert
Have you used Viread (tenofovir)?
Worth itNot sureNot worth it
More about ZeritSide effectsAlternativesFDA package insert
Have you used Zerit (stavudine)?
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