Compare Viread vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Viread
(tenofovir)

Zerit
(stavudine)

Works with other medicines to treat HIV infection. Also treats Hepatitis B Virus. tenofovir can be a good choice to take within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class. It may not be the best choice though for people with kidney problems.Works with other medicines to treat HIV infection. Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.
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Coupons for Viread
Best available price for 30 (300mg) tablets of tenofovir
Coupons for Zerit
Best available price for 60 (40mg) capsules of stavudine
Reviews & ratings
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Reviews for Viread (tenofovir)
Not enough review data. Review it!
of people (All ages) say Viread (tenofovir) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Viread (tenofovir)?
Worth itNot sureNot worth it
Reviews for Zerit (stavudine)
Not enough review data. Review it!
Same vs. Viread (tenofovir)
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Same vs. Viread (tenofovir)
Not enough review data. Review it!
Same vs. Viread (tenofovir)
Have you used Zerit (stavudine)?
Worth itNot sureNot worth it
Side effects
VireadZerit

We haven’t found good data for Viread side effects.

FDA side effect reports for Viread »

We haven’t found good data for Zerit side effects.

FDA side effect reports for Zerit »
How it works
VireadZerit
tenofovir stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.stavudine stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.
Type of medication
VireadZerit
Available as
VireadZerit
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for
VireadZerit
  • HIV Infection
  • HIV Infection
Risk factors for serious side effects
VireadZerit
  • Women
  • Obesity
  • Liver disease
  • Kidney damage
  • Prior bone fractures
Detailed Viread (tenofovir) risks & warnings »
  • Use of hydroxyurea, didanosine, and stavudine together
  • HIV
  • Exposure to other infections
  • Start of a new HIV medication
  • Change in HIV therapy
Detailed Zerit (stavudine) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
VireadZerit
No interactions related info.
  • Interacts with many different medications.
Food
VireadZerit
No food related info.
  • Take with or without food.
Kidneys and liver
VireadZerit
  • The dose of tenofovir depends on how your kidneys work. It is really important to consistently monitor them with your doctor.
  • Don't take other drugs that can hurt your kidneys while taking tenofovir without talking to your doctor. That sadly includes non-steroidal anti-inflammatory drugs (NSAIDs), like aspirin, Advil, and Aleve.
  • tenofovir can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use tenofovir. It may not be a good choice for people with liver problems.
  • Severe worsening of Hepatitis B has been seen in patients who have stopped taking tenofovir. Liver function should be closely watched in people who have both HIV and HBV.
  • tenofovir is removed from the body by the kidney. Kidney (renal) damage, including cases of renal failure and Fanconi syndrome (injury to the tubes inside of the kidney), has been reported with the use of tenofovir. Your doctor must continually monitor the function of your kidneys while you are taking tenofovir.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • stavudine can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use stavudine. It may not be a good choice for people with liver problems.
Upsides and benefits
VireadZerit
  • Take tenofovir once a day, with or without food.
  • For people who can't swallow the tablet, take the powder instead.
  • tenofovir is used for HIV in kids 2 years and older, and chronic hepatitis B in kids 12 years and older.
  • stavudine is provided as both capsules and an oral solution.
  • Take with or without food.
  • Can be used by patients on dialysis.
  • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides and risks
VireadZerit
  • The tenofovir powder can't be mixed in a liquid, so mix into soft food like applesauce and yogurt.
  • The dose of tenofovir depends on how your kidneys work. It is really important to consistently monitor them with your doctor.
  • Must take twice a day, every 12 hours.
  • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
  • Interacts with many different medications.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
Tips from our pharmacists for people taking the medication
VireadZerit
  • Don't take other drugs that can hurt your kidneys while taking tenofovir without talking to your doctor. That sadly includes non-steroidal anti-inflammatory drugs (NSAIDs), like aspirin, Advil, and Aleve.
  • People with HIV should be tested for Hepatitis B virus (HBV) before starting tenofovir.
  • Similarly, patients with chronic hepatitis B, should be tested for HIV before starting tenofovir.
  • Decreases in bone mineral density can happen while taking tenofovir.
  • Work with your doctor to monitor your kidney function and bone mineral density regularly.
  • Set a timer on your phone to make sure you don't forget to take stavudine at the right time.
  • Talk with your doctor about all other medications you are taking since stavudine interacts with many other drugs.
  • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking stavudine and report them to your doctor.
Learn more
More about VireadSide effectsAlternativesFDA package insert
Have you used Viread (tenofovir)?
Worth itNot sureNot worth it
More about ZeritSide effectsAlternativesFDA package insert
Have you used Zerit (stavudine)?
Worth itNot sureNot worth it