Compare Vivelle-Dot vs. Alora

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vivelle-Dot (Estradiol Patch)

Prescription only

Alora (estradiol patch)

Prescription only
Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

The Vivelle-Dot (Estradiol Patch) needs to be replaced twice a week, but it comes in more strengths than other patches. It may have fewer side effects than oral estrogen pills.

Relieves hot flashes and vaginal dryness due to menopause and strengthens your bones.

Alora (estradiol patch) treats symptoms from low estrogen, and it may have fewer side effects than oral estrogen pills.

Upsides
  • Comes in 4 different strengths.
  • The Vivelle-Dot (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
  • Improves mood, energy, and mental alertness for some people.
  • Alora (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to or can't take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy.
Downsides
  • You need to replace the Vivelle-Dot (Estradiol Patch) twice a week, compared to other patches that are once a week.
  • Patch can fall off.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Vivelle-Dot (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
  • You need to replace Alora (estradiol patch) twice a week, compared to other patches that are once a week.
  • Patches can fall off.
  • Increases your risk of uterine and breast cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
Used for
  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
  • Low estrogen
  • Primary ovarian failure
  • Prevention of postmenopausal osteoporosis
  • Treats hot flashes, night sweats and flushing in women in menopause
  • Treats vaginal changes in women in menopause
  • Treats low estrogen in women
  • Prevents bone thinning in women in menopause
Dosage forms
  • Patch
  • Patch
Price
Lowest price near you
$129.59
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Lowest price near you
$110.34
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Reviews
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Side effects
10possible side effects
  • Headache
    26%
  • Breast tenderness
    13%
  • Back pain
    11%
  • Intermenstrual bleeding
    11%
  • Influenza
    8%
  • Nasopharyngitis
    8%
  • Nausea
    5%
  • Pain
    5%
  • Sinusitis
    5%
  • Upper respiratory tract infection
    5%
See more detailed side effects
10possible side effects
  • Vaginal bleeding
    33%
  • Headache
    21%
  • Lung infection
    16%
  • Pain
    9%
  • Sinus infection
    8%
  • Vaginal inflammation
    8%
  • Breast pain
    7%
  • Back pain
    6%
  • Skin irritation
    6%
  • Accidental injury
    5%
See more detailed side effects
Risks and warnings
  • Endometrial cancer

    Using estrogen for more than one year

  • Breast cancer

    Personal or family history of breast cancer

    ...and 1 more risk factors

  • Increased risk of blood clots and stroke

    Personal or family history of blood clots

    ...and 2 more risk factors

  • Increased risk of heart disease

    Smoking

    ...and 5 more risk factors

  • Harm to fetus

    Women of childbearing age

  • Pancreas swelling (pancreatitis)

    High levels of triglycerides

See more detailed risks and warnings
  • Endometrial cancer

    Using estrogen for more than one year

  • Breast cancer

    Personal or family history of breast cancer

    ...and 1 more risk factors

  • Increased risk of blood clots and stroke

    Personal or family history of blood clots

    ...and 3 more risk factors

  • Increased risk of heart disease

    Smoking

    ...and 5 more risk factors

  • Dementia

    Age 65 or older

  • Pancreas swelling (pancreatitis)

    High levels of triglycerides

See more detailed risks and warnings