Compare Vytorin vs. Antara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

3.3/ 5 average rating with 99 reviewsforVytorin
Lowers cholesterol and triglycerides.

Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.

2.5/ 5 average rating with 56 reviewsforAntara
Upsides
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Antara (fenofibrate) can reduce triglycerides by about 20-50%.
  • Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
  • There is a less expensive generic version available.
  • You only need to take it once a day, with or without food.
Downsides
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
  • Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
  • Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
  • Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
56 reviews so far
27%
saidit'sworth it
14%
saiditworked well
29%
saidit'sa big hassle

Have you used Antara (fenofibrate)?

Leave a review
Side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
11possible side effects
  • Abnormal liver function tests
    8%
  • Respiratory disorder
    6%
  • Stomach pain
    5%
  • Back pain
    3%
  • Headache
    3%
  • Increased AST
    3%
  • Increased ALT
    3%
  • Increased creatine phosphokinase
    3%
  • Nausea
    2%
  • Constipation
    2%
  • Hay fever
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Asian patients taking high-dose niacin
  • Liver damage
    • Past history of liver disease
    • heavy alcohol use
  • High blood sugar
    • Diabetes
  • Increased risk for colds and flu
  • Skin reactions
  • Harm to fetus
    • Pregnancy
See more detailed risks and warnings
  • Muscle pain
    • Taking Antara (fenofibrate) with statins
    • Elderly patients
    • Patients with diabetes
    • Patients with a history of renal failure.
  • Liver damage
    • History of liver disease
  • Gallstones
    • History of gallstones
  • Increased bleeding risk
    • Taking Antara (fenofibrate) with anticoagulants
  • Inflammation of pancreas
  • Changes in blood tests
See more detailed risks and warnings