Compare Vytorin vs. Atorvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vytorin (Ezetimibe / Simvastatin)

Prescription only

Lipitor (atorvastatin)

Prescription only
Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

4.4/ 7 average rating with 99 reviewsforVytorin
Lowers cholesterol.

Lipitor (atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.

5.2/ 7 average rating with 1377 reviewsforAtorvastatin
Upsides
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lipitor (atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • It's one of the strongest cholesterol-lowering statin medications.
  • Lipitor (atorvastatin) is a good option for people who have high cholesterol and diabetes.
  • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
Downsides
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
  • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$91.93
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Lowest price near you
$10.55
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Reviews
99 
53%
think this treatment is worth it
36%
think this treatment works well
19%
think this treatment is a hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
1377 
63%
think this treatment is worth it
51%
think this treatment works well
13%
think this treatment is a hassle

Have you used Lipitor (atorvastatin)?

Leave a review
Side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
10possible side effects
  • Common cold
    8%
  • Joint pain
    7%
  • Diarrhea
    7%
  • Pain in the arms and legs
    6%
  • Urinary tract infection
    6%
  • Indigestion
    5%
  • Nausea
    4%
  • Musculoskeletal pain
    4%
  • Muscle Spasms
    4%
  • Myalgia
    4%
See more detailed side effects
Risks and warnings
  • Muscle pain

    Asian patients taking high-dose niacin

  • Liver damage

    Past history of liver disease

    ...and 1 more risk factors

  • High blood sugar

    Diabetes

  • Harm to fetus

    Pregnancy

See more detailed risks and warnings
  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Birth defects

    Pregnancy

  • Stroke

    History of hemorrhagic strokes

See more detailed risks and warnings