Compare Vytorin vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vytorin (Ezetimibe / Simvastatin)

Prescription only

Lopid (Gemfibrozil)

Prescription only
Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

4.4/ 7 average rating with 99 reviewsforVytorin
Lowers triglyceride levels.

Lopid (Gemfibrozil) is a generically available medication that can lower triglyceride levels by up to 50%.

Upsides
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Considered as a first choice medication for lowering triglyceride levels in the blood. Studies have shown it can reduce triglycerides by up to 50%.
  • Available as a generic.
  • Can be used with other medications, such as fish oil, to lower bad cholesterol and increase good cholesterol.
Downsides
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • While Lopid (Gemfibrozil) has been shown to lower triglycerides, it has not been shown by itself to reduce the number of deaths caused by high cholesterol.
  • Can't be used with statins to lower cholesterol because of the risk of muscle and kidney damage.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$91.93
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Lowest price near you
$14.15
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Reviews
99 
53%
think this treatment is worth it
36%
think this treatment works well
19%
think this treatment is a hassle

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Side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
The Lopid (Gemfibrozil) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Muscle pain

    Asian patients taking high-dose niacin

  • Liver damage

    Past history of liver disease

    ...and 1 more risk factors

  • High blood sugar

    Diabetes

  • Harm to fetus

    Pregnancy

See more detailed risks and warnings
  • Muscle pain

    Taking Lopid (Gemfibrozil) with statins

  • Liver damage

    Past history of liver disease

  • Increased bleeding risk

    Taking Lopid (Gemfibrozil) with anticoagulants

See more detailed risks and warnings