Compare Vytorin vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

3.3/ 5 average rating with 99 reviewsforVytorin
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

2.9/ 5 average rating with 68 reviewsforTrilipix
Upsides
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
68 reviews so far
50%
saidit'sworth it
22%
saiditworked well
25%
saidit'sa big hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
Side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Muscle pain
    • Asian patients taking high-dose niacin
  • Liver damage
    • Past history of liver disease
    • heavy alcohol use
  • High blood sugar
    • Diabetes
  • Increased risk for colds and flu
  • Skin reactions
  • Harm to fetus
    • Pregnancy
See more detailed risks and warnings
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings