Compare Vyvanse vs. Desoxyn

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vyvanse
(Lisdexamfetamine)

Desoxyn
(Methamphetamine)

Helps you focus and stay alert. Vyvanse (Lisdexamfetamine) is a first-choice treatment for ADHD and you only have to take it once a day. However, it's only available as brand name drug, so it can be expensive.Helps you focus and lose weight. Desoxyn (Methamphetamine) is an effective and cheap medication used to treat ADHD, but it can be habit-forming and is not used for long-term treatment.
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Reviews & ratings
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4.924276169265033Vyvanse
Reviews for Vyvanse (Lisdexamfetamine)
65%
of people say Vyvanse (Lisdexamfetamine) is worth it
46%
say it works well
18%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
VyvanseDesoxyn
  • Decreased appetite 35%
  • Dry mouth 23%
  • Sleep difficulty 19%
  • Any side effect 8%
  • Abdominal pain upper 6%
  • Vomiting 5%
  • Drowsiness 1%
  • Fever 1%
More Vyvanse side effects »

We haven’t found good data for Desoxyn side effects.

FDA side effect reports for Desoxyn »
How it works
VyvanseDesoxyn
Vyvanse (Lisdexamfetamine) is an amphetamine stimulant. Researchers don't know exactly how it works for ADHD, but it increases norepinephrine and dopamine activity in the brain, which affects attention and behavior.Desoxyn (Methamphetamine) is a stimulant. It treats attention-deficit/hyperactivity disorder (ADHD) and weight loss by increasing norepinephrine and dopamine activity in the brain.
Type of medication
VyvanseDesoxyn
StimulantPrescription only
StimulantPrescription only
Available as
VyvanseDesoxyn
  • Pill
  • Pill
Used for (click to learn more)
VyvanseDesoxyn
Risk factors for serious side effects
VyvanseDesoxyn
  • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
  • History of drug abuse
  • History of heart problems
  • History of psychotic episodes
  • History of Bipolar Disorder
  • Children ages 6 to 12
    Detailed Vyvanse (Lisdexamfetamine) risks & warnings »
    • History of heart problems
    • History of drug abuse
    • History of psychotic episodes
    • History of Bipolar Disorder
    • Children
    • History of seizures
    • Women of childbearing age
    • Breast-feeding
    • Taking MAO inhibitors, insulin and other high blood pressure medicine
    Detailed Desoxyn (Methamphetamine) risks & warnings »
    Pregnancy category
    VyvanseDesoxyn
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    • Don't take it with alcohol or drugs.
    No specific alcohol-related info.
    Food
    No specific food-related info.
    • If you're taking Desoxyn (Methamphetamine) for weight loss, take it 30 minutes before a meal. Desoxyn (Methamphetamine) can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Don't take Desoxyn (Methamphetamine) in the evening or you won't be able to sleep.
    Weight
    • Appetite suppression may occur. In clinical studies, long-term treatment with stimulants similar to Vyvanse (Lisdexamfetamine) caused a temporary slowing of growth rate (both height and weight) in children ages six to twelve years. Doctors should monitor children's growth during treatment.
    • Only recommended for weight loss if other medications and plans haven't worked.
    • If you're taking Desoxyn (Methamphetamine) for weight loss, take it 30 minutes before a meal. Desoxyn (Methamphetamine) can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Appetite suppression can occur. In clinical studies, long-term treatment with stimulants similar to Desoxyn (Methamphetamine) caused a temporary slowing of growth rate (both height and weight) in children who started the medication before they started puberty. Doctors should monitor children's growth during treatment.
    Upsides and benefits
    VyvanseDesoxyn
    • First-choice medication to treat ADHD.
    • Vyvanse (Lisdexamfetamine) is used in combination with counseling or other non-drug therapies to treat ADHD.
    • Usually dosed once a day, so parents don't need to send the medication with their children to school.
    • The capsule can be taken whole, or opened into a glass of water or orange juice, or swallowed in a spoonful of yogurt.
    • Recommended as a first-choice medication to treat ADHD in both adults and children.
    • Available as a generic, so it is cheaper than other medications to treat ADHD.
    Downsides and risks
    VyvanseDesoxyn
    • Has to be taken in the morning, otherwise it can cause insomnia later that night.
    • Not available as a generic medication, so it can be expensive.
    • It's a controlled medication and should be locked up to prevent potential abuse.
    • Not safe for people with a history of heart problems.
    • Only recommended for weight loss if other medications and plans haven't worked.
    • Only used for short-term treatment because it is habit-forming.
    • If you want to stop taking Desoxyn (Methamphetamine), talk to your doctor since stopping can cause withdrawal symptoms.
    • Not safe for use in children younger than 12 years.
    Tips from our pharmacists for people taking the medication
    VyvanseDesoxyn
    • Take Vyvanse (Lisdexamfetamine) early in the morning to prevent insomnia later that night.
    • Avoid driving the first few days that you take Vyvanse (Lisdexamfetamine) until you know how your body reacts to it.
    • Don't take it with alcohol or drugs.
    • Store it in a locked area to prevent abuse.
    • It can cause changes in your mood.
    • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
    • Don't take Desoxyn (Methamphetamine) in the evening or you won't be able to sleep.
    • If you're taking Desoxyn (Methamphetamine) for weight loss, take it 30 minutes before a meal. Desoxyn (Methamphetamine) can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Desoxyn (Methamphetamine) is only meant to be used for a few weeks since it can be habit-forming and lose its effectiveness.
    • Can cause reduced appetite, insomnia, and restlessness.
    Learn more
    More about VyvanseSide effectsReviews & ratingsAlternativesFDA package insert
    More about DesoxynSide effectsReviews & ratingsAlternativesFDA package insert