Compare Vyvanse vs. Strattera

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Strattera (Atomoxetine)

Prescription only
Helps you focus and stay alert.

Vyvanse (Lisdexamfetamine) is a first-choice treatment for ADHD and you only have to take it once a day. However, it's only available as brand name drug, so it can be expensive.

3.7/ 5 average rating with 491 reviewsforVyvanse
Helps you focus and stay alert.

Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.

3.2/ 5 average rating with 94 reviewsforStrattera
Upsides
  • First-choice medication to treat ADHD.
  • Vyvanse (Lisdexamfetamine) is used in combination with counseling or other non-drug therapies to treat ADHD.
  • Usually dosed once a day, so parents don't need to send the medication with their children to school.
  • The capsule can be taken whole, or opened into a glass of water or orange juice, or swallowed in a spoonful of yogurt.
  • One of the few medications used to treat ADHD that's not a stimulant.
  • It isn't a controlled substance.
  • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
  • You usually only need to take it once a day.
Downsides
  • Has to be taken in the morning, otherwise it can cause insomnia later that night.
  • Not available as a generic medication, so it can be expensive.
  • It's a controlled medication and should be locked up to prevent potential abuse.
  • Not safe for people with a history of heart problems.
  • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
  • It's only available as a brand name medication, so it can be expensive.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
491 reviews so far
67%
saidit'sworth it
49%
saiditworked well
17%
saidit'sa big hassle

Have you used Vyvanse (Lisdexamfetamine)?

Leave a review
94 reviews so far
46%
saidit'sworth it
32%
saiditworked well
24%
saidit'sa big hassle

Have you used Strattera (Atomoxetine)?

Leave a review
Side effects
18possible side effects
  • Decreased Appetite
    27%
  • Insomnia
    27%
  • Dry Mouth
    26%
  • Diarrhea
    7%
  • Nausea
    7%
  • Any side effect
    6%
  • Anxiety
    6%
  • Anorexia
    5%
  • Feeling Jittery
    4%
  • Agitation
    3%
  • Blood Pressure Increased
    3%
  • Hyperhidrosis
    3%
  • Restlessness
    3%
  • Weight Loss
    3%
  • Erectile dysfunction
    3%
  • Dyspnea
    2%
  • Heart Rate Increased
    2%
  • Tremor
    2%
See more detailed side effects
30possible side effects
  • Nausea
    26%
  • Dry mouth
    20%
  • Decreased appetite
    16%
  • Insomnia
    15%
  • Changes in heart rate or blood pressure
    10%
  • Fatigue
    10%
  • Constipation
    8%
  • Dizziness
    8%
  • Somnolence
    8%
  • Erectile dysfunction
    8%
  • Abdominal pain
    7%
  • Urinary hesitation
    6%
  • Irritability
    5%
  • Dyspepsia
    4%
  • Vomiting
    4%
  • Abnormal dreams
    4%
  • Ejaculation delayed and/or ejaculation disorder
    4%
  • Hyperhidrosis
    4%
  • Palpitations
    3%
  • Chills
    3%
  • Paraesthesia
    3%
  • Libido decreased
    3%
  • Sleep disorder
    3%
  • Dysmenhorrhea
    3%
  • Hot flush
    3%
  • Feeling jittery
    2%
  • Thirst
    2%
  • Weight loss
    2%
  • Dysuria
    2%
  • Any sexual side effect
    2%
See more detailed side effects
Risks and risk factors
  • High blood pressure
    • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
  • Abuse and dependence
    • History of drug abuse
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of Bipolar Disorder
  • Long-term growth suppression
    • Children ages 6 to 12
  • Circulation problems in the hands and feet
See more detailed risks and warnings
  • Suicidal thinking
    • Age below 18
  • Liver disease
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of Bipolar Disorder
  • Prolonged erection
  • Problems with urination
  • Long-term growth suppression
    • Starting Strattera (Atomoxetine) before puberty
See more detailed risks and warnings