Compare Xalatan vs. Simbrinza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Xalatan
(Latanoprost)

Simbrinza
(Brinzolamide / Brimonidine)

Lowers eye pressure. Xalatan (Latanoprost) lowers high pressure in the eye well and helps prevent glaucoma.lowers eye pressure Simbrinza ia an effective two medicine combination that is used when one medication alone is not effective, and you are looking for ease of using both medications in one drop.
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Reviews & ratings
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Side effects
XalatanSimbrinza

We haven’t found good data for Xalatan side effects.

FDA side effect reports for Xalatan »

We haven’t found good data for Simbrinza side effects.

FDA side effect reports for Simbrinza »
How it works
XalatanSimbrinza
Xalatan (Latanoprost) reduces high pressure inside the eye. If not treated, the pressure can cause glaucoma and eventual blindness.Simbrinza decreases the production of fluids within the eye, and increases the flow of fluids out of the eye.
Type of medication
XalatanSimbrinza
Anti-glaucoma
Prostaglandin agonist
Prescription only
Coming soon.
Available as
XalatanSimbrinza
  • Eye drops
  • Eye drops
Used for (click to learn more)
XalatanSimbrinza
  • Ocular hypertension Open-angle glaucoma
Risk factors for serious side effects
XalatanSimbrinza
  • Replacing contact lenses to soon
  • Long term use
Detailed Xalatan (Latanoprost) risks & warnings »
Coming soon.
Pregnancy category
XalatanSimbrinza
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
XalatanSimbrinza
  • It's easy to use and you only need to give yourself one drop each day in the evening.
  • Can be used along with other eye drops, if needed for better results.
  • Xalatan (Latanoprost) is available generically.
  • Xalatan (Latanoprost) can increase the length, thickness, and number of your eyelashes.
  • Simbrinza may be more effective because it contains two medications
  • It is easier to take two medications in one drop.
Downsides and risks
XalatanSimbrinza
  • Xalatan (Latanoprost) can turn the colored part of your eye and your eyelashes brown.
  • Simbrinza may cause carbonated beverages to taste metallic..
  • You must wait 5 minutes before using another eye drop
  • Remove contact lenses and leave out for 15 minutes after using the the eyedrop
  • Not used in children under 2 years of age
Tips from our pharmacists for people taking the medication
XalatanSimbrinza
  • Wash your hands before putting drops in your eyes.
  • Don't touch the dropper tip to your eye or with your hands.
  • If you wear contacts, remove them and wait 15 minutes after putting the drop in your eye, to put your contacts back in.
  • After putting drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
  • If using this with another eyedrop medication, wait five minutes between using them.
  • Wash hands before putting drops in eyes.
  • Do not touch the dropper tip to your eye or hands.
  • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
  • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
Learn more
More about XalatanSide effectsReviews & ratingsAlternativesFDA package insert
More about SimbrinzaSide effectsReviews & ratingsAlternativesFDA package insert