Compare Xanax vs. chlordiazepoxide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Xanax
(alprazolam)

Librium
(chlordiazepoxide)

Helps you relax. Xanax (Alprazolam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and longer-term for panic attacks. More likely to cause withdrawal symptoms compared to similar drugs.Reduces anxiety. Librium (chlordiazepoxide) is good for lowering anxiety since its effects aren't as strong as similar medicines; however, it lasts longer in the body and can be more dangerous in older people.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Xanax
Best available price for 60 (0.5mg) tablets of xanax
Coupons for chlordiazepoxide
Best available price for 60 (25mg) capsules of chlordiazepoxide
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.35Xanax
Reviews for Xanax
74%
of people (All ages) say Xanax is worth it
55%
say it works well
13%
say it's a big hassle
1287 reviews
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Librium (chlordiazepoxide)?
Worth itNot sureNot worth it
Side effects
Xanaxchlordiazepoxide
  • Drowsiness 34%
  • Fatigue and tiredness 6%
  • Impaired coordination 23%
  • Irritability 3%
  • Memory impairment 11%
  • Increased appetite 10%
More Xanax side effects »

The chlordiazepoxide FDA package insert doesn’t have numbers about how common side effects are.

More about chlordiazepoxide side effects »
How it works
Xanaxchlordiazepoxide
Xanax (Alprazolam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Librium (chlordiazepoxide) is a benzodiazepine. It's not clear how Librium (chlordiazepoxide) treats anxiety, but it possibly calms activity in a part of the brain that's responsible for emotional responses.
Type of medication
Xanaxchlordiazepoxide
Prescription onlyPrescription only
Available as
Xanaxchlordiazepoxide
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
  • Pill
Used for
Xanaxchlordiazepoxide
Risk factors for serious side effects
Xanaxchlordiazepoxide
  • History of drug abuse
  • Taking with alcohol or drugs
  • Taking more than 4 mg/day or longer than 12 weeks
  • Stopping Xanax (Alprazolam) suddenly
  • Severely depressed
Detailed Xanax (alprazolam) risks & warnings »
  • Taking Librium (chlordiazepoxide) for more than 2 weeks
  • Drinking alcohol or taking narcotics
Detailed Librium (chlordiazepoxide) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Xanaxchlordiazepoxide
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Don't drink alcohol or take any narcotics while taking Librium (chlordiazepoxide) since it can slow your breathing.
Kidneys and liver
Xanaxchlordiazepoxide
  • Processed by the liver, so might not be the best choice if you have liver problems.
No kidneys and liver related info.
Sleep
Xanaxchlordiazepoxide
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
No sleep related info.
Upsides and benefits
Xanaxchlordiazepoxide
  • Effective at relieving short-term anxiety.
  • Effective longer-term for panic attacks.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Librium (chlordiazepoxide) is available as a generic.
  • Because Librium (chlordiazepoxide) lasts longer in the body, it's preferred for alcohol withdrawal since it's less likely to cause seizures.
  • Librium (chlordiazepoxide) can be used by itself, or with antidepressants to help lower anxiety.
Downsides and risks
Xanaxchlordiazepoxide
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
  • Librium (chlordiazepoxide) lasts much longer in older people, so it's not safe to use if you're age 65 or older.
  • Librium (chlordiazepoxide) is not as strong as similar medicines, so it's only really useful to calm anxiety and for alcohol withdrawal.
  • Librium (chlordiazepoxide) can be addictive, so you should use it for as short of a time as possible.
Tips from our pharmacists for people taking the medication
Xanaxchlordiazepoxide
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 45 minutes when swallowed.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
  • Don't drink alcohol or take any narcotics while taking Librium (chlordiazepoxide) since it can slow your breathing.
  • You should take Librium (chlordiazepoxide) for as short amount of time as possible to treat your anxiety. Librium (chlordiazepoxide) can be addictive.
  • If you've taken Librium (chlordiazepoxide) for a long time, don't stop taking it suddenly without talking to your doctor first. It can be very dangerous.
  • Don't drive or do anything requiring concentration while taking Librium (chlordiazepoxide) since it can make you sleepy. This can be worse if you drink alcohol or take narcotics.
Learn more
More about XanaxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it
More about chlordiazepoxideSide effectsAlternativesFDA package insert
Have you used Librium (chlordiazepoxide)?
Worth itNot sureNot worth it