Compare Xanax vs. Vistaril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Xanax
(Alprazolam)

Vistaril
(Hydroxyzine Pamoate)

Helps you relax. Xanax (Alprazolam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and longer-term for panic attacks. More likely to cause withdrawal symptoms compared to similar drugs.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.35Xanax
Reviews for Xanax (Alprazolam)
74%
of people (All ages) say Xanax (Alprazolam) is worth it
55%
say it works well
13%
say it's a big hassle
1287 reviews
Have you used Xanax (Alprazolam)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Vistaril (Hydroxyzine Pamoate)?
Worth itNot sureNot worth it
Side effects
XanaxVistaril

The Xanax FDA package insert doesn’t have numbers about how common side effects are.

More about Xanax side effects »

We haven’t found good data for Vistaril side effects.

FDA side effect reports for Vistaril »
How it works
XanaxVistaril
Xanax (Alprazolam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Coming soon.
Type of medication
XanaxVistaril
Anti-anxiety
Benzodiazepine
Prescription only
Coming soon.
Available as
XanaxVistaril
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
XanaxVistaril
  • Anxiety Pruritus Sedation; Adjunct
Risk factors for serious side effects
XanaxVistaril
  • History of drug abuse
  • Taking with alcohol or drugs
  • Taking more than 4 mg/day or longer than 12 weeks
  • Stopping Xanax (Alprazolam) suddenly
  • Severely depressed
Detailed risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
XanaxVistaril
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Not safe to use with alcohol.
No alcohol related info.
Kidneys and liver
XanaxVistaril
  • Processed by the liver, so might not be the best choice if you have liver problems.
No kidneys and liver related info.
Sleep
XanaxVistaril
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can cause temporary dizziness and drowsiness.
No sleep related info.
Upsides and benefits
XanaxVistaril
  • Effective at relieving short-term anxiety.
  • Effective longer-term for panic attacks.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
Coming soon
Downsides and risks
XanaxVistaril
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
Coming soon
Tips from our pharmacists for people taking the medication
XanaxVistaril
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 45 minutes when swallowed.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
Coming soon
Learn more
More about XanaxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Xanax (Alprazolam)?
Worth itNot sureNot worth it
More about VistarilSide effectsReviews & ratingsFDA package insert
Have you used Vistaril (Hydroxyzine Pamoate)?
Worth itNot sureNot worth it