Compare Zantac vs. Maalox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zantac 75 (ranitidine)

Prescription or OTC
Relieves heartburn and stomach ulcers.

Zantac 75 (ranitidine) is an effective and inexpensive medicine for hearburn with few side effects, but may interfere with other drugs.

5.1/ 7 average rating with 1062 reviewsforZantac
Relieves heartburn and indigestion.

Maalox (aluminum / magnesium / simethicone) gives quick relief for heartburn, gas, and bloating, but it may not be as effective or last as long as other antacids.

4.6/ 7 average rating with 213 reviewsforMaalox
Upsides
  • Zantac 75 (ranitidine) works well to relieve heartburn symtoms and is quite tolerable.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • If you have trouble swallowing pills you may find the liquid product a good option.
  • Inexpensive with over-the-counter and generic options.
  • Coupons are available for the brand product - speak to your doctor or pharmacist.
  • Works quickly.
  • Inexpensive and available over-the-counter.
  • Is one of the first choice medications for heartburn relief if you are pregnant.
Downsides
  • Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. Speak to your doctor or pharmacist if you need quicker relief.
  • Zantac 75 (ranitidine) does not last as long as some other acid reducers. Speak to your doctor or pharmacist if you need longer relief.
  • May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. Your doctor will assess which medication is best for you.
  • Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. Your doctor can order lab tests to monitor your vitamin B12 levels.
  • Doesn't last very long. Talk to your doctor or pharmacist if you need longer lasting relief.
  • Is not a good option if you have frequent symptoms (more than 2 times a week). Talk to your doctor or pharmacist about stronger medications.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Oral syrup
  • Injection
  • Chewable tablet
  • Liquid
No pricing information available
No pricing information available
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Reviews
1062 
72%
think this treatment is worth it
44%
think this treatment works well
7%
think this treatment is a hassle

Have you used Zantac 75 (ranitidine)?

Leave a review
213 
69%
think this treatment is worth it
30%
think this treatment works well
9%
think this treatment is a hassle

Have you used Maalox (aluminum / magnesium / simethicone)?

Leave a review
Side effects
The Zantac 75 (ranitidine) FDA package insert doesn’t have numbers about how common side effects are.
The Maalox (aluminum / magnesium / simethicone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Confusion

    Aged 60 years or older

    ...and 2 more risk factors

  • Acute porphyria

    Acute Porphyria

  • Chronic lung problems

    Asthma

    ...and 2 more risk factors

See more detailed risks and warnings
  • Aluminum and magnesium overdose

    Kidney problems

    ...and 1 more risk factors

See more detailed risks and warnings