Compare Zegerid vs. Maalox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zegerid
(omeprazole / sodium bicarbonate)

Maalox
(aluminum / magnesium / simethicone)

Relieves heartburn, ulcers, and acid tummy. Zegerid (Omeprazole / Sodium Bicarbonate) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Relieves heartburn and acid tummy. Maalox (Aluminum / Magnesium / Simethicone) gives quick relief for heartburn, gas, and bloating. It may not be as effective or last as long as alternative antacids though.
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Coupons for Zegerid
Best available price for 30 (40mg/1100mg) capsules of zegerid
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.24Zegerid
Reviews for Zegerid
72%
of people (All ages) say Zegerid is worth it
55%
say it works well
12%
say it's a big hassle
Have you used Zegerid (omeprazole / sodium bicarbonate)?
Worth itNot sureNot worth it
Reviews for Maalox
69%
+3% better vs. Zegerid
30%
+25% better vs. Zegerid
9%
-3% worse vs. Zegerid
213 reviews
Have you used Maalox (aluminum / magnesium / simethicone)?
Worth itNot sureNot worth it
Side effects
ZegeridMaalox

The Zegerid FDA package insert doesn’t have numbers about how common side effects are.

More about Zegerid side effects »

We haven’t found good data for Maalox side effects.

FDA side effect reports for Maalox »
How it works
ZegeridMaalox
Zegerid (Omeprazole / Sodium Bicarbonate) is a type of antacid called a proton pump inhibitor. It blocks the release of acid in your stomach, which treats heartburn and helps ulcers heal.Maalox (Aluminum / Magnesium / Simethicone) is a combination medicine for stomach trouble. Aluminum and magnesium are antacids that relieve heartburn and acid tummy (indigestion). Simethicone relieves gas and bloating.
Type of medication
ZegeridMaalox
Prescription or OTCOver-the-counter
Available as
ZegeridMaalox
  • Pill
  • Chewable tablet
  • Liquid
Used for
ZegeridMaalox
Risk factors for serious side effects
ZegeridMaalox
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Zegerid (omeprazole / sodium bicarbonate) risks & warnings »
  • Age 65 or older
  • Current kidney disease
Detailed Maalox (aluminum / magnesium / simethicone) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Interactions
ZegeridMaalox
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
No interactions related info.
Food
ZegeridMaalox
  • Take 1 hour before a meal.
  • Take 1-3 hours after a meal.
Kidneys and liver
ZegeridMaalox
No kidneys and liver related info.
  • People with kidney disease may need to avoid Maalox. Ask your doctor.
  • If you have kidney disease Maalox (Aluminum / Magnesium / Simethicone) can build up in your blood. This may can cause toxic levels of aluminum or magnesium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Maalox (Aluminum / Magnesium / Simethicone); a different antacid would be better for you.
Upsides and benefits
ZegeridMaalox
  • Most people can take Zegerid without any noticeable day-to-day side effects.
  • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Works really fast.
  • Available over the counter without a prescription.
  • Cheap.
Downsides and risks
ZegeridMaalox
  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
  • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Zegerid long-term.
  • Although the generic is affordable, other medications might still be cheaper than Zegerid.
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
  • Doesn't last very long.
  • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
  • Some people don't care for the taste.
Tips from our pharmacists for people taking the medication
ZegeridMaalox
  • Take 1 hour before a meal.
  • Don't chew or crush capsules; swallow them whole.
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
  • If you've been having heartburn for 3 months or more, talk to your doctor before taking Zegerid. Get a check-up to make sure you aren't having a more serious stomach problem.
  • Talk to your doctor if you're still having heartburn after two weeks of use. Don't keep taking Zegerid; get checked-out first.
  • Take 1-3 hours after a meal.
  • Take 1-2 hours apart from other medication that you take by mouth.
  • Tell your doctor if you have severe diarrhea or constipation.
  • People with kidney disease may need to avoid Maalox. Ask your doctor.
Learn more
More about ZegeridSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zegerid (omeprazole / sodium bicarbonate)?
Worth itNot sureNot worth it
More about MaaloxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Maalox (aluminum / magnesium / simethicone)?
Worth itNot sureNot worth it