Compare Zegerid vs. Maalox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves heartburn and excess stomach acid, and treats ulcers.

Zegerid (omeprazole and sodium bicarbonate) is an effective medicine for heartburn, but it's more expensive than buying omeprazole by itself.

3.8/ 5 average rating with 74 reviewsforZegerid
Relieves heartburn and indigestion.

Maalox (aluminum / magnesium / simethicone) gives quick relief for heartburn, gas, and bloating, but it may not be as effective or last as long as other antacids.

3.4/ 5 average rating with 213 reviewsforMaalox
Upsides
  • Most people can take Zegerid without any noticeable day-to-day side effects.
  • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you may only need to take it once a day.
  • Contains both a quick acting and a long acting component to help provide fast and long lasting relief.
  • Is inexpensive as both generic and over-the-counter options are availabe.
  • Works quickly.
  • Inexpensive and available over-the-counter.
  • Is one of the first choice medications for heartburn relief if you are pregnant.
Downsides
  • Zegerid (omeprazole and sodium bicarbonate) contains sodium bicarbonate which isn't good if your doctor's asked you to lower your sodium bicarbonate or if you have heart or blood pressure problems.
  • May not be the best option if you have Bartter's syndrome due to sodium bicarbonate. Speak to your doctor first.
  • Should not be used for occasional heartburns. Talk to your doctor or pharmacist about other medications if you do not have frequent heartburns.
  • Doesn't last very long. Talk to your doctor or pharmacist if you need longer lasting relief.
  • Is not a good option if you have frequent symptoms (more than 2 times a week). Talk to your doctor or pharmacist about stronger medications.
Used for
Dosage forms
  • Pill
  • Suspension
  • Chewable tablet
  • Liquid
Price
Lowest price
$3103.61
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Reviews
74 reviews so far
72%
saidit'sworth it
55%
saiditworked well
12%
saidit'sa big hassle

Have you used Zegerid (omeprazole and sodium bicarbonate)?

Leave a review
213 reviews so far
69%
saidit'sworth it
30%
saiditworked well
9%
saidit'sa big hassle

Have you used Maalox (aluminum / magnesium / simethicone)?

Leave a review
Side effects
The Zegerid (omeprazole and sodium bicarbonate) FDA package insert doesn’t have numbers about how common side effects are.
The Maalox (aluminum / magnesium / simethicone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Severe diarrhea
    • Elderly
    • Use during hospitalization
  • Bone fractures
    • Long-term use of Zegerid (omeprazole and sodium bicarbonate)
    • Using high doses of Zegerid (omeprazole and sodium bicarbonate)
  • Drug interactions
  • Chronic lung problems
    • Asthma
    • COPD
    • Lung problems
  • Low vitamin or mineral levels
  • Lupus
See more detailed risks and warnings
  • Long term use
  • Aluminum and magnesium overdose
    • Kidney problems
    • Taking more than the recommended daily maximum
  • Drug interactions
See more detailed risks and warnings