Compare Zegerid vs. Tums

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zegerid
(omeprazole / sodium bicarbonate)

Tums
(calcium carbonate)

Relieves heartburn, ulcers, and acid tummy. Zegerid (Omeprazole / Sodium Bicarbonate) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.
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Coupons for Zegerid
Best available price for 30 (40mg/1100mg) capsules of zegerid
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.24Zegerid
Reviews for Zegerid
72%
of people (All ages) say Zegerid is worth it
55%
say it works well
12%
say it's a big hassle
Have you used Zegerid (omeprazole / sodium bicarbonate)?
Worth itNot sureNot worth it
Reviews for Tums
82%
-10% worse vs. Zegerid
43%
+12% better vs. Zegerid
5%
-7% worse vs. Zegerid
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Side effects
ZegeridTums

The Zegerid FDA package insert doesn’t have numbers about how common side effects are.

More about Zegerid side effects »

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »
How it works
ZegeridTums
Zegerid (Omeprazole / Sodium Bicarbonate) is a type of antacid called a proton pump inhibitor. It blocks the release of acid in your stomach, which treats heartburn and helps ulcers heal.Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.
Type of medication
ZegeridTums
Prescription or OTCOver-the-counter
Available as
ZegeridTums
  • Pill
  • Chewable tablet
  • Liquid
Used for
ZegeridTums
Risk factors for serious side effects
ZegeridTums
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Zegerid (omeprazole / sodium bicarbonate) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    ZegeridTums
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
    No interactions related info.
    Food
    ZegeridTums
    • Take 1 hour before a meal.
    No food related info.
    Kidneys and liver
    ZegeridTums
    No kidneys and liver related info.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    Upsides and benefits
    ZegeridTums
    • Most people can take Zegerid without any noticeable day-to-day side effects.
    • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    Downsides and risks
    ZegeridTums
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Zegerid long-term.
    • Although the generic is affordable, other medications might still be cheaper than Zegerid.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    Tips from our pharmacists for people taking the medication
    ZegeridTums
    • Take 1 hour before a meal.
    • Don't chew or crush capsules; swallow them whole.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
    • If you've been having heartburn for 3 months or more, talk to your doctor before taking Zegerid. Get a check-up to make sure you aren't having a more serious stomach problem.
    • Talk to your doctor if you're still having heartburn after two weeks of use. Don't keep taking Zegerid; get checked-out first.
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    Learn more
    More about ZegeridSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zegerid (omeprazole / sodium bicarbonate)?
    Worth itNot sureNot worth it
    More about TumsSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tums (calcium carbonate)?
    Worth itNot sureNot worth it