Compare Zestoretic vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers blood pressure.

Lisinopril/hydrochlorothiazide is a good 2-in-1 blood pressure-lowering medicine that protects kidney function.

3.4/ 5 average rating with 294 reviewsforZestoretic
Lowers blood pressure and controls heart rate.

Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.

3.5/ 5 average rating with 406 reviewsforCoreg
Upsides
  • Combination medicine for people with high blood pressure. Doctors might prescribe it when you need more than one medicine to control your blood pressure.
  • The two drugs in Lisinopril/hydrochlorothiazide work together to lower blood pressure, remove extra water from your body, and lower your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides
  • Comes in fixed dosage strengths, so it's harder for your doctor to adjust your dose.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Makes you urinate more often.
  • Doesn't work as well in people with severe kidney problems.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
294 reviews so far
51%
saidit'sworth it
40%
saiditworked well
17%
saidit'sa big hassle

Have you used Zestoretic (Lisinopril / Hydrochlorothiazide)?

Leave a review
406 reviews so far
53%
saidit'sworth it
46%
saiditworked well
18%
saidit'sa big hassle

Have you used Coreg (Carvedilol)?

Leave a review
Side effects
11possible side effects
  • Dizziness
    8%
  • Headache
    5%
  • Cough
    4%
  • Fatigue
    4%
  • Orthostatic Effects
    3%
  • Diarrhea
    3%
  • Nausea
    2%
  • Upper Respiratory Infection
    2%
  • Muscle Cramps
    2%
  • Asthenia
    2%
  • Paresthesia
    2%
See more detailed side effects
5possible side effects
  • Dizziness
    6%
  • Bradycardia
    2%
  • Postural hypotension
    2%
  • Insomnia
    2%
  • Diarrhea
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Unusual tongue swelling
    • African descent
  • Severe allergic reactions while on dialysis
    • People requiring high flux dialysis
  • Acute kidney failure
    • History of kidney disease
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
  • Cough
See more detailed risks and warnings
  • Worsened chest pain; increased risk of heart attack and heart rhythm problems
    • Abrupt discontinuation of Coreg (Carvedilol)
  • Slowing of the heart rate
  • Low blood pressure
  • Worsening heart failure
    • Congestive heart failure
    • Increasing the dose of Coreg (Carvedilol)
  • Masked symptoms of low blood sugar
    • Diabetes
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Masked symptoms of overactive thyroid
See more detailed risks and warnings