Compare Zetia vs. Antara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia
(Ezetimibe)

Antara
(Fenofibrate)

Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.
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Reviews & ratings
Button Group. All currently active
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4.393700787401575Zetia
Reviews for Zetia (Ezetimibe)
42%
of people say Zetia (Ezetimibe) is worth it
34%
say it works well
20%
say it's a big hassle
Reviews for Antara (Fenofibrate)
27%
15% vs. Zetia (Ezetimibe)
14%
20% vs. Zetia (Ezetimibe)
29%
9% vs. Zetia (Ezetimibe)
Side effects
ZetiaAntara
  • Ear, nose, or throat infection 1%
  • Sinus inflammation 1%
  • Arthtralgia 1%
More Zetia side effects »
  • Abnormal liver function tests 7%
  • Increased ast 2%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
  • Constipation 1%
  • Increased alt 1%
More Antara side effects »
How it works
ZetiaAntara
Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).
Type of medication
ZetiaAntara
Cholesterol-lowering
Cholesterol inhibitor
Prescription only
Cholesterol-lowering
Fibric acid
Prescription only
Available as
ZetiaAntara
  • Pill
  • Pill
Used for (click to learn more)
ZetiaAntara
Risk factors for serious side effects
ZetiaAntara
    • Taking Zetia (Ezetimibe) with statins
    • Past history of liver disease
    • Taking Zetia (Ezetimibe) with statins
    Detailed Zetia (Ezetimibe) risks & warnings »
    • Taking Antara (Fenofibrate) with statins
    • Past history of liver disease
      • Taking Antara (Fenofibrate) with anticoagulants
              Detailed Antara (Fenofibrate) risks & warnings »
              Pregnancy category
              ZetiaAntara
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              Alcohol
              No specific alcohol-related info.
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Don't drink a lot of alcohol while taking this medicine.
              Food
              No specific food-related info.No specific food-related info.
              Kidneys and liver
              • People on Zetia (Ezetimibe) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
              • People on Antara (Fenofibrate) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
              Sex
              No specific sex-related info.No specific sex-related info.
              Sleep
              No specific sleep-related info.No specific sleep-related info.
              Weight
              No specific weight-related info.No specific weight-related info.
              Upsides and benefits
              ZetiaAntara
              • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Can be used with other medicines to improve cholesterol.
              • Available in a combination pill with simvastatin.
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              Downsides and risks
              ZetiaAntara
              • Doesn't lower triglycerides (fats).
              • Hasn't been shown to lower the risk of heart attacks or heart disease.
              • By itself, Zetia is not as effective as statins for improving cholesterol.
              • There's no generic available, so it can be expensive.
              • In studies, it didn't lower heart disease in people with Type 2 diabetes.
              • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Different forms and strengths of this medication can't be substituted for each other.
              Tips from our pharmacists for people taking the medication
              ZetiaAntara
              • Lowers bad cholesterol, and raises good cholesterol.
              • Tell your doctor if you develop bone or muscle pain.
              • Can be used with other medications to lower cholesterol.
              • May cause diarrhea or raise your chance of getting colds.
              • Lowers triglycerides.
              • Can cause backache or headache.
              • Call your doctor if you develop muscle or abdominal pain.
              • Don't drink a lot of alcohol while taking this medicine.
              • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
              • You should use this medicine in combination with a healthy diet.
              Learn more
              More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert
              More about AntaraSide effectsReviews & ratingsAlternativesFDA package insert