Compare Zetia vs. Antara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia
(Ezetimibe)

Antara
(Fenofibrate)

Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.393700787401575Zetia
Reviews for Zetia (Ezetimibe)
42%
of people (All ages) say Zetia (Ezetimibe) is worth it
34%
say it works well
20%
say it's a big hassle
127 reviews
Have you used Zetia (Ezetimibe)?
Worth itNot sureNot worth it
Reviews for Antara (Fenofibrate)
27%
15% vs. Zetia (Ezetimibe)
14%
20% vs. Zetia (Ezetimibe)
29%
9% vs. Zetia (Ezetimibe)
Have you used Antara (Fenofibrate)?
Worth itNot sureNot worth it
Side effects
ZetiaAntara
  • Ear, nose, or throat infection 1%
  • Sinus inflammation 1%
  • Arthtralgia 1%
More Zetia side effects »
  • Abnormal liver function tests 7%
  • Increased ast 2%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
  • Constipation 1%
  • Increased alt 1%
More Antara side effects »
How it works
ZetiaAntara
Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).
Type of medication
ZetiaAntara
Cholesterol-lowering
Cholesterol inhibitor
Prescription only
Cholesterol-lowering
Fibric acid
Prescription only
Available as
ZetiaAntara
  • Pill
  • Pill
Used for (click to learn more)
ZetiaAntara
Risk factors for serious side effects
ZetiaAntara
    • Taking Zetia (Ezetimibe) with statins
    • Past history of liver disease
    • Taking Zetia (Ezetimibe) with statins
    Detailed Zetia (Ezetimibe) risks & warnings »
    • Taking Antara (Fenofibrate) with statins
    • Past history of liver disease
      • Taking Antara (Fenofibrate) with anticoagulants
              Detailed Antara (Fenofibrate) risks & warnings »
              Pregnancy

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Alcohol
              ZetiaAntara
              No alcohol related info.
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Don't drink a lot of alcohol while taking this medicine.
              Kidneys and liver
              ZetiaAntara
              • Reports of liver disease have been reported in people who take Zetia (Ezetimibe), especially if taken with statins. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.
              • Reports of liver damage have been reported in people who take Antara (Fenofibrate), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
              Upsides and benefits
              ZetiaAntara
              • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Can be used with other medicines to improve cholesterol.
              • Available in a combination pill with simvastatin.
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              Downsides and risks
              ZetiaAntara
              • Doesn't lower triglycerides (fats).
              • Hasn't been shown to lower the risk of heart attacks or heart disease.
              • By itself, Zetia is not as effective as statins for improving cholesterol.
              • There's no generic available, so it can be expensive.
              • In studies, it didn't lower heart disease in people with Type 2 diabetes.
              • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Different forms and strengths of this medication can't be substituted for each other.
              Tips from our pharmacists for people taking the medication
              ZetiaAntara
              • Lowers bad cholesterol, and raises good cholesterol.
              • Tell your doctor if you develop bone or muscle pain.
              • Can be used with other medications to lower cholesterol.
              • May cause diarrhea or raise your chance of getting colds.
              • Lowers triglycerides.
              • Can cause backache or headache.
              • Call your doctor if you develop muscle or abdominal pain.
              • Don't drink a lot of alcohol while taking this medicine.
              • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
              • You should use this medicine in combination with a healthy diet.
              Learn more
              More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert
              Have you used Zetia (Ezetimibe)?
              Worth itNot sureNot worth it
              More about AntaraSide effectsReviews & ratingsAlternativesFDA package insert
              Have you used Antara (Fenofibrate)?
              Worth itNot sureNot worth it