Compare Zetia vs. Omega 3 Acid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia
(ezetimibe)

Lovaza
(omega-3 acid)

Lowers cholesterol. Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.41Zetia
Reviews for Zetia
42%
of people (All ages) say Zetia is worth it
34%
say it works well
21%
say it's a big hassle
128 reviews
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it
Reviews for Omega 3 Acid
59%
-17% worse vs. Zetia
50%
-16% worse vs. Zetia
28%
+7% better vs. Zetia
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it
Side effects
ZetiaOmega 3 Acid
  • Common cold 1%
  • Sore throat 4%
  • Sinus infection 1%
  • Abnormal liver tests 3%
  • Joint pain 1%
  • Pain in arms and legs 1%
  • Muscle pain 3%
More Zetia side effects »
  • Eructation 3%
  • Change in taste 4%
  • Indigestion 1%
More Omega 3 Acid side effects »
How it works
ZetiaOmega 3 Acid
Zetia (ezetimibe) is a cholesterol-lowering medicine. It stops your body from absorbing cholesterol in food and helps process other forms of cholesterol.Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.
Type of medication
ZetiaOmega 3 Acid
Prescription onlyPrescription only
Available as
ZetiaOmega 3 Acid
  • Pill
  • Pill
Used for
ZetiaOmega 3 Acid
Risk factors for serious side effects
ZetiaOmega 3 Acid
  • Taking Zetia (ezetimibe) with statins
  • Past history of liver disease
Detailed Zetia (ezetimibe) risks & warnings »
  • Allergy to fish or shellfish
  • Atrial fibrillation
Detailed Lovaza (omega-3 acid) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
ZetiaOmega 3 Acid
No food related info.
  • Take it with food.
  • You have to take it with food.
Kidneys and liver
ZetiaOmega 3 Acid
  • Zetia (ezetimibe) can hurt your liver, especially if it is used with statins. Talk to your doctor if you have liver disease.
No kidneys and liver related info.
Upsides and benefits
ZetiaOmega 3 Acid
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
  • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
  • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
Downsides and risks
ZetiaOmega 3 Acid
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
  • You can't take it if you're allergic to fish or shellfish.
  • You have to take it with food.
Tips from our pharmacists for people taking the medication
ZetiaOmega 3 Acid
  • Lowers bad cholesterol and raises good cholesterol.
  • Tell your doctor if you develop bone or muscle pain.
  • Can be used with other medications to lower cholesterol.
  • Good alternative to statins if you can't tolerate statins or are unable to control cholesterol with statins alone.
  • Can cause diarrhea or increase your chance of getting colds.
  • Lowers triglycerides.
  • Take it with food.
  • Swallow capsules whole.
  • Can cause burping and changes in taste.
  • Don't use if you have an allergy to fish or shellfish.
  • You should use this medicine in combination with a healthy diet.
Learn more
More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it
More about Omega 3 AcidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it