Compare Zetia vs. Omega 3 Acid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia
(ezetimibe)

Lovaza
(omega-3 acid)

Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.
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Prices and coupon for 30 (10mg) tablets of ezetimibe
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.41Zetia
Reviews for Zetia (ezetimibe)
42%
of people (All ages) say Zetia (ezetimibe) is worth it
34%
say it works well
21%
say it's a big hassle
128 reviews
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it
Reviews for Lovaza (omega-3 acid)
59%
+17% better vs. Zetia (ezetimibe)
50%
+16% better vs. Zetia (ezetimibe)
28%
-7% worse vs. Zetia (ezetimibe)
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it
Side effects
ZetiaOmega 3 Acid
  • Ear, nose, or throat infection 1%
  • Sinus inflammation 1%
  • Arthtralgia 1%
More Zetia side effects »
  • Eructation 3%
  • Change in taste 4%
  • Indigestion 1%
More Omega 3 Acid side effects »
How it works
ZetiaOmega 3 Acid
Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.
Type of medication
ZetiaOmega 3 Acid
Prescription only
Prescription only
Available as
ZetiaOmega 3 Acid
  • Pill
  • Pill
Used for
ZetiaOmega 3 Acid
Risk factors for serious side effects
ZetiaOmega 3 Acid
    • Taking Zetia (Ezetimibe) with statins
    • Past history of liver disease
    • Taking Zetia (Ezetimibe) with statins
    Detailed Zetia (ezetimibe) risks & warnings »
    • Allergy to fish or shellfish
    • Atrial fibrillation
    Detailed Lovaza (omega-3 acid) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    ZetiaOmega 3 Acid
    No food related info.
    • You have to take it with food.
    • Take it with food.
    Kidneys and liver
    ZetiaOmega 3 Acid
    • Reports of liver disease have been reported in people who take Zetia (Ezetimibe), especially if taken with statins. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.
    No kidneys and liver related info.
    Upsides and benefits
    ZetiaOmega 3 Acid
    • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
    • Can be used with other medicines to improve cholesterol.
    • Available in a combination pill with simvastatin.
    • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
    • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
    Downsides and risks
    ZetiaOmega 3 Acid
    • Doesn't lower triglycerides (fats).
    • Hasn't been shown to lower the risk of heart attacks or heart disease.
    • By itself, Zetia is not as effective as statins for improving cholesterol.
    • There's no generic available, so it can be expensive.
    • You can't take it if you're allergic to fish or shellfish.
    • You have to take it with food.
    Tips from our pharmacists for people taking the medication
    ZetiaOmega 3 Acid
    • Lowers bad cholesterol, and raises good cholesterol.
    • Tell your doctor if you develop bone or muscle pain.
    • Can be used with other medications to lower cholesterol.
    • May cause diarrhea or raise your chance of getting colds.
    • Lowers triglycerides.
    • Take it with food.
    • Swallow capsules whole.
    • Can cause burping and changes in taste.
    • Don't use if you have an allergy to fish or shellfish.
    • You should use this medicine in combination with a healthy diet.
    Learn more
    More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zetia (ezetimibe)?
    Worth itNot sureNot worth it
    More about Omega 3 AcidSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Lovaza (omega-3 acid)?
    Worth itNot sureNot worth it