› Reports of liver disease have been reported in people who take Zetia (Ezetimibe), especially if taken with statins. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.
› Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
Upsides and benefits
› Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
› Can be used with other medicines to improve cholesterol.
› Available in a combination pill with simvastatin.
› Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
› Good medicine for lowering triglycerides.
Downsides and risks
› Doesn't lower triglycerides (fats).
› Hasn't been shown to lower the risk of heart attacks or heart disease.
› By itself, Zetia is not as effective as statins for improving cholesterol.
› There's no generic available, so it can be expensive.
› In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
› Different forms and strengths of this medication can't be substituted for each other.
Tips from our pharmacists for people taking the medication
› Lowers bad cholesterol, and raises good cholesterol.
› Tell your doctor if you develop bone or muscle pain.
› Can be used with other medications to lower cholesterol.
› May cause diarrhea or raise your chance of getting colds.
› Can be used with other medications to help lower cholesterol.
› Lowers triglycerides.
› Can raise your chance of getting colds and flu.
› Call your doctor if you develop muscle or abdominal pain.
› Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.