Compare Zetia vs. Vytorin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia (ezetimibe)

Prescription only
Lowers cholesterol.

Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.

4.4/ 7 average rating with 128 reviewsforZetia
Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

4.4/ 7 average rating with 99 reviewsforVytorin
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
Downsides
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$26.45
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Lowest price near you
$91.93
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Reviews
128 
42%
think this treatment is worth it
34%
think this treatment works well
21%
think this treatment is a hassle

Have you used Zetia (ezetimibe)?

Leave a review
99 
53%
think this treatment is worth it
36%
think this treatment works well
19%
think this treatment is a hassle

Have you used Vytorin (Ezetimibe / Simvastatin)?

Leave a review
Side effects
8possible side effects
  • Diarrhea
    4%
  • Common cold
    4%
  • Sore throat
    4%
  • Sinus infection
    3%
  • Joint pain
    3%
  • Pain in arms and legs
    3%
  • Muscle pain
    3%
  • Abnormal liver tests
    3%
See more detailed side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
Risks and warnings
  • Muscle pain

    Taking Zetia (ezetimibe) with statins

  • Abnormal liver blood tests

    Past history of liver disease

    ...and 1 more risk factors

See more detailed risks and warnings
  • Muscle pain

    Asian patients taking high-dose niacin

  • Liver damage

    Past history of liver disease

    ...and 1 more risk factors

  • High blood sugar

    Diabetes

  • Harm to fetus

    Pregnancy

See more detailed risks and warnings