Compare Ziac vs. Dutoprol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

(Bisoprolol / Hydrochlorothiazide)

(Metoprolol Succinate / Hydrochlorothiazide)

Coming soon.Lowers blood pressure. Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) helps lower blood pressure by working in two different ways in your body. It's good for stubbornly high blood pressure.
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Reviews & ratings
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Side effects

We haven’t found good data for Ziac side effects.

FDA side effect reports for Ziac »
  • Common cold 2%
  • Fatigue 2%
  • Back pain 1%
More Dutoprol side effects »
How it works
Coming soon.Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) is a combination medicine that helps control your blood pressure and reduce the risk of a heart attack or stroke. Hydrochlorothiazide is a diuretic that removes extra water from your body. Metoprolol is a beta blocker that lowers your heart rate.
Type of medication
Coming soon.
Beta blocker
Prescription only
Available as
  • Pill
  • Pill
Used for (click to learn more)
  • Hypertension
Risk factors for serious side effects
Coming soon.
  • Sudden discontinuation of medicine
  • History of asthma
  • History of diabetes
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
  • Current electrolyte imbalance
  • History of gout
  • Current kidney problems
Detailed Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) risks & warnings »
Pregnancy category
No specific alcohol-related info.No specific alcohol-related info.
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
  • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
No specific sex-related info.No specific sex-related info.
No specific sleep-related info.No specific sleep-related info.
No specific weight-related info.No specific weight-related info.
Upsides and benefits
Coming soon.
  • Lowers the risk of heart attack and stroke.
  • Combines the benefits of two blood pressure-lowering medicines in a single pill.
  • Helpful in getting rid of extra fluids in your body.
Downsides and risks
Coming soon.
  • Not the first choice to lower blood pressure.
  • Brand only, can be more expensive.
  • Can make you urinate more often and feel out of breath during physical activities, which may not go away.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Forgetting to take the medicine or stopping it suddenly can cause a heart attack.
Tips from our pharmacists for people taking the medication
Coming soon.
  • Makes you urinate more often, so don't take it too close to bedtime.
  • Can make you feel dizzy or short of breath the first few days, but this should improve as your body gets used to the medicine.
  • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
  • Tell your doctor about any cold-like symptoms, dizziness, headache, fatigue, or muscle weakness that doesn't go away.
  • Don't stop taking this medicine suddenly since it can trigger heart problems.
Learn more
More about ZiacSide effectsReviews & ratingsFDA package insert
More about DutoprolSide effectsReviews & ratingsAlternativesFDA package insert