Compare Ziagen vs. Videx

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ziagen (abacavir)

Prescription only

Videx (Didanosine Or Ddl)

Prescription only
Works with other medicines to treat HIV infection.

Ziagen (abacavir) is a first-choice medication that is used with others to treat HIV. It's important that your doctor test you for allergic reactions to Ziagen (abacavir) before starting the medication.

Works with other medicines to treat HIV infection.

Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, Videx can be a difficult drug to take. Videx has numerous serious side effects. It is also difficult taking Videx twice a day on an empty stomach.

Upsides
  • Ziagen (abacavir) is found in many other combination tablets.
  • Ziagen (abacavir) has few drug interactions.
  • People whose kidneys are not working as well can still take Ziagen (abacavir) without having to change its dose.
  • Kids 3 months and older can use Ziagen (abacavir).
  • The oral solution can be stored in the refrigerator for up to 30 days.
  • While Videx doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides
  • Ziagen (abacavir) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver problems.
  • Severe allergic reactions have happened in some patients taking Ziagen (abacavir). Your doctor will test you for any possible risk of reaction before starting Ziagen (abacavir).
  • Must take on an empty stomach at least 30 minutes before, or 2 hours after eating.
  • Take twice a day.
  • The amount of Videx you will take is based on your body weight, kidney, and liver function.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
Used for
  • HIV infection
Dosage forms
  • Pill
  • Liquid
  • Extended release
  • Liquid
  • Pill
Price
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Reviews
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Side effects
21possible side effects
  • Nausea
    19%
  • Headache
    13%
  • Fatigue and discomfort
    12%
  • Dreams/sleep disorders
    10%
  • Nausea and vomiting
    10%
  • Severe allergic reactions
    9%
  • Fever and/or chills
    9%
  • Headaches/migraine
    7%
  • Diarrhea
    7%
  • Skin rashes
    7%
  • Rashes
    6%
  • Stomach pain
    6%
  • Depression
    6%
  • Dizziness
    6%
  • Muscle and joint pain
    6%
  • Ear/nose/throat infections
    5%
  • Viral respiratory infections
    5%
  • Anxiety
    5%
  • Bronchitis
    4%
  • Pneumonia
    4%
  • Vomiting
    2%
See more detailed side effects
The Videx (Didanosine Or Ddl) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Severe allergic reactions
    • Positive genetic test (HLA B5701)
  • Lactic acidosis & severe liver damage
    • Obesity
    • Women
    • History of liver problems
  • Immune system reactivation
  • Fat redistribution
  • Heart attack
    • High blood pressure
    • High cholesterol
    • Diabetes
See more detailed risks and warnings
  • Pancreatitis
    • Kidney problems
    • Use of stavudine, another HIV drug
  • Lactic acidosis
    • Women
    • Use of stavudine, another HIV drug
  • Liver damage
    • Use of hydroxyurea, stavudine, and Videx together
  • Peripheral neuropathy
    • Use of stavudine, another HIV drug
  • Eye changes
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Fat Redistribution
    • HIV treatment
See more detailed risks and warnings