Compare Ziagen vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Works with other medicines to treat HIV infection.

Ziagen (abacavir) is a first-choice medication that is used with others to treat HIV. It's important that your doctor test you for allergic reactions to Ziagen (abacavir) before starting the medication.

Works with other medicines to treat HIV infection.

Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.

Upsides
  • Ziagen (abacavir) is found in many other combination tablets.
  • Ziagen (abacavir) has few drug interactions.
  • People whose kidneys are not working as well can still take Ziagen (abacavir) without having to change its dose.
  • Kids 3 months and older can use Ziagen (abacavir).
  • stavudine is provided as both capsules and an oral solution.
  • Take with or without food.
  • Can be used by patients on dialysis.
  • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides
  • Ziagen (abacavir) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver problems.
  • Severe allergic reactions have happened in some patients taking Ziagen (abacavir). Your doctor will test you for any possible risk of reaction before starting Ziagen (abacavir).
  • Must take twice a day, every 12 hours.
  • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
  • Interacts with many different medications.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
Used for
  • HIV infection
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
Price
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Reviews
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Side effects
21possible side effects
  • Nausea
    19%
  • Headache
    13%
  • Fatigue and discomfort
    12%
  • Dreams/sleep disorders
    10%
  • Nausea and vomiting
    10%
  • Severe allergic reactions
    9%
  • Fever and/or chills
    9%
  • Headaches/migraine
    7%
  • Diarrhea
    7%
  • Skin rashes
    7%
  • Rashes
    6%
  • Stomach pain
    6%
  • Depression
    6%
  • Dizziness
    6%
  • Muscle and joint pain
    6%
  • Ear/nose/throat infections
    5%
  • Viral respiratory infections
    5%
  • Anxiety
    5%
  • Bronchitis
    4%
  • Pneumonia
    4%
  • Vomiting
    2%
See more detailed side effects
The Zerit (Stavudine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Severe allergic reactions
    • Positive genetic test (HLA B5701)
  • Lactic acidosis & severe liver damage
    • Obesity
    • Women
    • History of liver problems
  • Immune system reactivation
  • Fat redistribution
  • Heart attack
    • High blood pressure
    • High cholesterol
    • Diabetes
See more detailed risks and warnings
  • Lactic acidosis
  • Pancreatitis
  • Liver damage
    • Use of hydroxyurea, didanosine, and stavudine together
  • Peripheral neuropathy
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Fat Redistribution
    • HIV treatment
See more detailed risks and warnings