Compare Zofran vs. Sancuso

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zofran
(ondansetron)

Sancuso
(granisetron)

Helps you feel less queasy. Zofran (Ondansetron) works well to prevent nausea and vomiting, and it's available in different forms that you don't have to swallow.Coming soon.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.91Zofran
Reviews for Zofran
66%
of people (All ages) say Zofran is worth it
51%
say it works well
15%
say it's a big hassle
366 reviews
Have you used Zofran (ondansetron)?
Worth itNot sureNot worth it

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Have you used Sancuso (granisetron)?
Worth itNot sureNot worth it
Side effects
ZofranSancuso
  • Headache 2%
  • Constipation 11%
  • Fever 5%
  • Increased ast and alt 5%
  • Drowsiness 4%
  • Itching 2%
  • Tingling sensation 2%
More Zofran side effects »

We haven’t found good data for Sancuso side effects.

FDA side effect reports for Sancuso »
How it works
ZofranSancuso
Zofran (Ondansetron) is an antiemetic (anti-nausea medicine). It works by blocking the nerves that cause your nausea and vomiting reflex.Coming soon.
Type of medication
ZofranSancuso
Prescription only
Available as
ZofranSancuso
  • Pill
  • Dissolving tablet
  • Liquid
  • Sublingual film
  • Pill
  • Liquid
  • Patch
Used for
ZofranSancuso
  • Chemotherapy Induced Nausea And Vomiting
Risk factors for serious side effects
ZofranSancuso
  • Long QT syndrome
Detailed Zofran (ondansetron) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Interactions
    ZofranSancuso
    • Can interact with antidepressants.
    No interactions related info.
    Upsides and benefits
    ZofranSancuso
    • Available in generic.
    • Available in forms that you don't have to swallow (like a tablet or film that dissolves in your mouth) if you're having trouble keeping anything down.
    • Starts working fast (in 30 minutes.
    Coming soon
    Downsides and risks
    ZofranSancuso
    • Can cause headaches.
    • Can interact with antidepressants.
    • Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
    Coming soon
    Tips from our pharmacists for people taking the medication
    ZofranSancuso
    • If you're using the disintegrating tablet, make sure your hands are dry first, peel off the foil and remove the tablet. Place the tablet on the tongue to let it dissolve naturally, then swallow. Don't drink water or anything else.
    • Can cause headache, fatigue or constipation.
    • If you're taking the oral film, don't chew or swallow it. Let it dissolve naturally on the tongue.
    • It takes 30 minutes for Zofran to start working.
    Coming soon
    Learn more
    More about ZofranSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zofran (ondansetron)?
    Worth itNot sureNot worth it
    More about SancusoSide effectsFDA package insert
    Have you used Sancuso (granisetron)?
    Worth itNot sureNot worth it