Compare Zomig vs. ergotamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zomig
(zolmitriptan)

Ergomar
(ergotamine)

Treats migraines. Triptans are the first-choice to treat migraines. Zomig (zolmitriptan) works just as well as other triptans for migraines.Treats migraine headaches. Ergomar (ergotamine) has more side effects than other medicines used to treat migraines.
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Best available price for 1 (3 tablets of 5mg) dose pack of zomig
Reviews & ratings
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Have you used Zomig (zolmitriptan)?
Worth itNot sureNot worth it

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Have you used Ergomar (ergotamine)?
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Side effects
Zomigergotamine
  • Nervous system problems 7%
  • Stomach problems 8%
  • Pain and pressure sensation 7%
  • Unusual sensations 6%
  • Nausea 5%
  • Dizziness 4%
  • Tingling or prickling sensation 5%
  • Neck, throat or jaw pain/pressure 4%
  • Sleepiness 3%
  • Warm or cold sensation 1%
More Zomig side effects »

The ergotamine FDA package insert doesn’t have numbers about how common side effects are.

More about ergotamine side effects »
How it works
Zomigergotamine
Zomig (zolmitriptan) is a triptan. It prevents the enlargement of blood vessels in your brain, which causes migraines.Ergomar (ergotamine) is an ergot alkaloid. It tightens the blood vessels in your brain to relieve the pain of your headaches.
Type of medication
Zomigergotamine
Prescription onlyPrescription only
Available as
Zomigergotamine
  • Pill
  • Dissolving tablet
  • Nasal spray
  • Dissolving pill
Used for
Zomigergotamine
Risk factors for serious side effects
Zomigergotamine
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Zomig (zolmitriptan) or other migraine treatment medications for 10 or more days a month
Detailed Zomig (zolmitriptan) risks & warnings »
  • Macrolide antibiotics
  • Protease inhibitors
  • Taking Ergomar (ergotamine) more than the recommended amount daily or weekly
  • Taking Ergomar (ergotamine) regularly for months
Detailed Ergomar (ergotamine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Upsides and benefits
Zomigergotamine
  • Zomig (zolmitriptan) is is a first choice treatment to treat severe migraines.
  • There are different forms of Zomig (zolmitriptan) available, including a dissolving pill and a nasal spray if you have trouble swallowing during a migraine attack.
  • The regular and dissolving pill forms of Zomig (zolmitriptan) are available as generics.
  • Ergomar (ergotamine) works better than other medicines if your migraines last more than 2 days or if you have more frequent migraines.
Downsides and risks
Zomigergotamine
  • If you're taking the nasal spray form of Zomig (zolmitriptan), you have to follow the instructions exactly or you won't get the full dose of medicine.
  • The nasal spray form of Zomig (zolmitriptan) is only available as brand name, so it can be expensive.
  • If you have heart disease or history of stroke, Zomig (zolmitriptan) may not be the best choice for you. Talk to your doctor about your medical history.
  • Harmful to the fetus so avoid if you're pregnant or think you may be pregnant.
  • Doesn't prevent migraines from happening. It can only relieve them.
  • Excessive use can be dangerous and result in rebound headaches. Talk to your doctor if your headaches are worse and occurring more frequently.
  • May not be right for you if you have high blood pressure or had a heart attack.
Tips from our pharmacists for people taking the medication
Zomigergotamine
  • Doesn't prevent migraines.
  • Use as soon as you feel a migraine starting. You can take another dose 2 hours later, but don't take more than 10 mg total in 24 hours.
  • Don't use it excessively since it can cause you to have more headaches. Talk to your doctor if you are having more than 4 migraines in a month.
  • Avoid if you're pregnant or think you may be pregnant since it can harm the fetus.
  • Take as soon as you feel the migraine coming on.
  • You may be more sensitive to cold since Ergomar (ergotamine) affects the circulation of your blood. Dress warmly.
  • Don't use Ergomar (ergotamine) excessively. The most you can take is 3 tablets per day or 5 tablets per week.
  • Don't use with triptans if you're taking Ergomar (ergotamine).
  • Talk to your doctor if you have heart disease or blood vessel problems before starting Ergomar (ergotamine).
Learn more
More about ZomigSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zomig (zolmitriptan)?
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More about ergotamineSide effectsAlternativesFDA package insert
Have you used Ergomar (ergotamine)?
Worth itNot sureNot worth it