Compare Zyprexa vs. Invega

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zyprexa (olanzapine)

Prescription only

Invega (paliperidone)

Prescription only
Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

5.1/ 7 average rating with 68 reviewsforZyprexa
Helps control your thoughts and mood.

Invega (paliperidone) relieves psychotic symptoms and improves mood.

4.2/ 7 average rating with 34 reviewsforInvega
Upsides
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
  • Won't make you as sleepy as other antipsychotic medicines.
  • If you have heart or kidney problems, this may be a better option than other antipsychotic medicines.
  • The pill and injection form allows for flexible dosing schedule.
Downsides
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
  • Side-effects of weight gain and hormonal imbalance may be intolerable for younger patients.
  • Frequent blood tests are sometimes required to check how the medicine is affecting your body.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Injection
  • Pill
  • Injection
Price
Lowest price near you
$12.05
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Lowest price near you
$2439.52
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Reviews
68 
41%
think this treatment is worth it
51%
think this treatment works well
51%
think this treatment is a hassle

Have you used Zyprexa (olanzapine)?

Leave a review
34 
29%
think this treatment is worth it
32%
think this treatment works well
35%
think this treatment is a hassle

Have you used Invega (paliperidone)?

Leave a review
Side effects
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
10possible side effects
  • Difficulty controlling movements
    12%
  • Drowsiness
    8%
  • Indigestion
    6%
  • Inability to be still
    6%
  • Nausea
    5%
  • Constipation
    4%
  • Weight gain
    4%
  • Abdominal discomfort
    3%
  • Common cold
    3%
  • Back pain
    3%
See more detailed side effects
Risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Higher blood sugar, high cholesterol, and weight gain

    People with diabetes

    ...and 1 more risk factors

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Higher blood sugar and cholesterol and weight gain

    Diabetes

    ...and 1 more risk factors

  • Difficulty concentrating

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings