Compare Zyrtec vs. Dimetapp Cold And Allergy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zyrtec (Cetirizine)

Prescription or OTC
Treats allergy symptoms.

Zyrtec (Cetirizine) is a once-daily allergy relief medication that won't make you feel too sleepy.

5.2/ 7 average rating with 1232 reviewsforZyrtec
Relieves congestion and allergy symptoms for kids.

Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is good for multiple nasal symptoms, but it can make you really drowsy.

4.5/ 7 average rating with 24 reviewsforDimetapp Cold And Allergy
Upsides
  • Zyrtec (Cetirizine) works as well as other antihistamines to treat sneezing and runny nose, but causes less sedation.
  • Works well to also treat hives and itchy skin.
  • Zyrtec (Cetirizine) is available over the counter without a prescription.
  • It comes as a tablet, liquid, and quick-dissolving tablet.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It's okay to take with most other medications because it has few drug interactions.
  • Most people don't get any side effects from Zyrtec (Cetirizine).
  • Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine with a decongestant and an antihistamine that's helpful in treating nasal symptoms related to cold and allergy.
  • Brompheniramine (the antihistamine) is useful for itchy eyes, runny nose, or constant sneezing.
  • Phenylephrine (the decongestant) is good for relieving congestion.
Downsides
  • Although it works fast, its effectiveness wears off for some people over time.
  • Zyrtec (Cetirizine) can be slightly more sedating than Allegra or Claritin.
  • Some people find that other more sedating antihistamines, like Benadryl, are more effective for them than Zyrtec (Cetirizine).
  • If you have daily allergy symptoms, a prescription nasal steroid spray might be better for you long-term.
  • If you don't really need both of the medications in this combination, you'd be taking extra medicine and might have extra side effects for no reason.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • Phenylephrine (the decongestant) doesn't last as long as other oral decongestants like pseudoephedrine, but can cause jitteriness.
  • The two medications in this medicine can somewhat work against each other, with one making you sleepy and the other making you jittery.
Used for
Dosage forms
  • Pill
  • Liquid capsule
  • Dissolving tablet
  • Liquid
  • Chewable tablet
  • Liquid
No pricing information available
No pricing information available
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Reviews
1232 
76%
think this treatment is worth it
47%
think this treatment works well
7%
think this treatment is a hassle

Have you used Zyrtec (Cetirizine)?

Leave a review
24 
58%
think this treatment is worth it
29%
think this treatment works well
8%
think this treatment is a hassle

Have you used Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine)?

Leave a review
Side effects
The Zyrtec (Cetirizine) FDA package insert doesn’t have numbers about how common side effects are.
The Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased side effects

    Age 65 or older

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Overdosage

    Current kidney disease

    ...and 1 more risk factors

See more detailed risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Harm to fetus

    Women of childbearing age

  • High blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Antihistamine side effects

    Age 65 years or older

    ...and 2 more risk factors

See more detailed risks and warnings