Mental health disorders

Restless legs syndrome

(RLS)

About Restless legs syndrome

Restless legs syndrome (RLS) causes a powerful urge to move your legs. Your legs become uncomfortable when you are lying down or sitting. Some people describe it as a creeping, crawling, tingling, or burning sensation. Moving makes your legs feel better, but not for long. RLS can make it hard to fall asleep and stay asleep.

In most cases, there is no known cause for RLS. In other cases, RLS is caused by a disease or condition, such as anemia or pregnancy. Some medicines can also cause temporary RLS. Caffeine, tobacco, and alcohol may make symptoms worse.

Lifestyle changes, such as regular sleep habits, relaxation techniques, and moderate exercise during the day can help. If those don't work, medicines may reduce the symptoms of RLS.

Most people with RLS also have a condition called periodic limb movement disorder (PLMD). PLMD is a condition in which a person's legs twitch or jerk uncontrollably, usually during sleep. PLMD and RLS can also affect the arms.

NIH: National Heart, Lung, and Blood Institute

Top Medications for Restless legs syndrome according to our users

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  • All men

  • Brand (generic)% of users who said medication was worth it
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  • All women

  • Brand (generic)% of users who said medication was worth it
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All Medications for Restless legs syndrome

  • Pain reliever > GABA analog

    • Horizant
      (Gabapentin enacarbil)
      Prescription only

      Horizant (Gabapentin Enacarbil) is a good way to treat pain since it can be used with other pain medications and it's not addictive. You'll need to stop drinking alcohol and it can be somewhat expensive.

      Was it worth it?
      • Available dosage forms:
      • Pill
  • Antihypertensive > Alpha agonist

    • Kapvay
      (Clonidine)
      Prescription only

      Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.

      Was it worth it?
      • Available dosage forms:
      • Extended release
  • Anti-anxiety > Benzodiazepine

    • Klonopin
      (Clonazepam)
      Prescription only

      Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.

      • Available dosage forms:
      • Pill
      • Dissolving tablet
  • Anti-parkinson > Dopamine agonist

    • Mirapex
      (Pramipexole)
      Prescription only

      Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

      Was it worth it?
      • Available dosage forms:
      • Pill
      • Extended release
    • Requip
      (Ropinirole)
      Prescription only

      Requip (Ropinirole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

      Was it worth it?
      • Available dosage forms:
      • Pill
      • Extended release

Medication side effects for Restless legs syndrome

These are some of the most common side effects from clinical trials for abdominal pain upper.

  • Mirapex: 4%
0 of 100

At this end, no one is expected to have abdominal pain upper

100 of 100

At this end, almost everyone is expected to have abdominal pain upper

Tips, success stories, and coping strategies for Restless legs syndrome

What tip would you give someone like me who was just diagnosed?
  • Don't start taking medications if you can get by. Over time your symptoms will worsen if you take prescriptions to help with RLS.
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Besides medications, what else has worked for you?

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