Mental health disorders

Smoking cessation

(Nicotine dependence)

About Smoking cessation

Tobacco use is the most common preventable cause of death. About half of the people who don't quit smoking will die of smoking-related problems. Quitting smoking is important for your health.

Soon after you quit, your circulation begins to improve, and your blood pressure starts to return to normal. Your sense of smell and taste return, and it's easier for you to breathe. In the long term, giving up tobacco can help you live longer. Your risk of getting cancer decreases with each year you stay smoke-free.

Quitting is not easy. You may have short-term affects such as weight gain, irritability, and anxiety. Some people try several times before they succeed. There are many ways to quit smoking. Some people stop "cold turkey." Others benefit from step-by-step manuals, counseling, or medicines or products that help reduce nicotine addiction. Your health care provider can help you find the best way for you to quit.

NIH: National Cancer Institute

Top Medications for Smoking cessation according to our users

Button Group. All currently active

All Medications for Smoking cessation

  • Smoking cessation > Partial nicotine agonist

    • Chantix
      (Varenicline)
      Prescription only

      Chantix (Varenicline) is a great way to help you quit smoking and stay off cigarettes, even though many people have nausea with it.

      Was it worth it?
      • Available dosage forms:
      • Pill
  • Antidepressant > Norepinephrine-dopamine reuptake inhibitor

    • Wellbutrin
      (Bupropion)
      Prescription only

      Wellbutrin (Bupropion) is good for treating depression and has fewer sexual side effects than other antidepressants, but you need to be okay with avoiding alcohol.Will Wellbutrin work for you?

      • Available dosage forms:
      • Pill
      • Extended release
  • Antidepressant > Smoking cessation

    • Zyban
      (Bupropion)
      Prescription only

      Good for blocking the withdrawal symptoms of quitting smoking. But you need to be okay with avoiding alcohol use and possibly using nicotine replacement.

      • Available dosage forms:
      • Pill
      • Extended release
  • Antidepressant > Tricyclic antidepressant (TCA)

    • Pamelor
      (Nortriptyline)
      Prescription only

      Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.

      Was it worth it?
      • Available dosage forms:
      • Pill
      • Liquid
  • Antihypertensive > Alpha agonist

    • Catapres
      (Clonidine)
      Prescription only

      Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.

      • Available dosage forms:
      • Pill
      • Extended release
      • Patch
    • Kapvay
      (Clonidine)
      Prescription only

      Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.

      Was it worth it?
      • Available dosage forms:
      • Extended release

Medication side effects for Smoking cessation

These are some of the most common side effects from clinical trials for abdominal pain.

  • Zyban: 3%
0 of 100

At this end, no one is expected to have abdominal pain

100 of 100

At this end, almost everyone is expected to have abdominal pain

Tips, success stories, and coping strategies for Smoking cessation

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