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Abilify Alternatives

(Aripiprazole)

  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
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Compare Abilify (Aripiprazole) to alternatives

These medications are comparable to Abilify (Aripiprazole) or used for similar purposes.

Abilify
(Aripiprazole)

Risperdal
(Risperidone)

Haldol
(Haloperidol)

Seroquel
(Quetiapine)

Zyprexa
(Olanzapine)

Invega
(Paliperidone)

Helps control your thoughts and mood. Abilify (Aripiprazole) is good for treating psychosis and mania, and can help with depression. Less likely to cause side effects than any other antipsychotic, but has a risk of suicidal thoughts for people age 24 and younger.Helps control your thoughts and mood. Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.Helps control your thoughts and calms agitation. Haldol (Haloperidol) is okay for treating psychosis and agitation. It's less likely to cause weight gain than other antipsychotics, but it's more likely to cause other bad side effects.Helps control your thoughts and mood. Seroquel (Quetiapine) is good for treating psychosis and mania. Fewer side effects than most antipsychotics, but might be less effective for people over age 40 with schizophrenia.Helps control your thoughts and mood. Zyprexa (Olanzapine) is good for treating psychosis, mania, and agitation. More likely to cause weight gain and sleepiness than other antipsychotics.Helps control your thoughts and mood. Invega (Paliperidone) is good for treating psychosis and improving mood. It's more likely to cause hormone problems than other antipsychotics.
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Reviews & ratings
Button Group. All currently active
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4.150943396226415Abilify
Reviews for Abilify (Aripiprazole)
42%
of people say Abilify (Aripiprazole) is worth it
38%
say it works well
35%
say it's a big hassle
Reviews for Risperdal (Risperidone)
48%
+6% vs. Abilify (Aripiprazole)
41%
+3% vs. Abilify (Aripiprazole)
48%
13% vs. Abilify (Aripiprazole)
Reviews for Haldol (Haloperidol)
37%
5% vs. Abilify (Aripiprazole)
41%
+3% vs. Abilify (Aripiprazole)
35%
Same vs. Abilify (Aripiprazole)
Reviews for Seroquel (Quetiapine)
52%
+10% vs. Abilify (Aripiprazole)
46%
+8% vs. Abilify (Aripiprazole)
28%
+7% vs. Abilify (Aripiprazole)
Reviews for Zyprexa (Olanzapine)
45%
+3% vs. Abilify (Aripiprazole)
53%
+15% vs. Abilify (Aripiprazole)
47%
12% vs. Abilify (Aripiprazole)
Reviews for Invega (Paliperidone)
30%
12% vs. Abilify (Aripiprazole)
33%
5% vs. Abilify (Aripiprazole)
30%
+5% vs. Abilify (Aripiprazole)
Side effects
AbilifyRisperdalHaldolSeroquelZyprexaInvega
  • Drowsiness 20%
  • Extrapyramidal disorder 17%
  • Relaxation or sleepiness 17%
  • Fatigue 15%
  • Restlessness 9%
  • Fever 8%
  • Vomiting 7%
  • Decreased appetite 5%
  • Excessive saliva 5%
  • Sleep difficulty 5%
More Abilify side effects »
  • Relaxation or sleepiness 48%
  • Increased appetite 29%
  • Fatigue 22%
  • Parkinsonism 17%
  • Constipation 11%
  • Dizziness 11%
  • Abdominal pain upper 11%
  • Common cold 10%
  • Nausea 9%
  • Indigestion 8%
More Risperdal side effects »

The Haldol FDA package insert doesn’t have numbers about how common side effects are.

More about Haldol side effects »
  • Drowsiness 42%
  • Dry mouth 31%
  • Dizziness 17%
  • Fatigue 10%
  • Increased appetite 9%
  • Headache 7%
  • Nausea 6%
  • Constipation 6%
  • Muscle weakness 6%
  • Positional low blood pressure 5%
More Seroquel side effects »
  • Relaxation or sleepiness 39%
  • Increased appetite 25%
  • Weight increase 22%
  • Drowsiness 22%
  • Dry mouth 15%
  • Dizziness 12%
  • Muscle weakness 9%
  • Fatigue 8%
  • Constipation 6%
  • Indigestion 6%
More Zyprexa side effects »
  • Abnormally fast heart beat 7%
  • Anxiety 5%
  • Common cold 4%
  • Indigestion 4%
  • Constipation 3%
  • Positional low blood pressure 3%
  • Muscle weakness 3%
  • Headache 2%
  • Nausea 2%
  • Abdominal discomfort 2%
More Invega side effects »
How it works
AbilifyRisperdalHaldolSeroquelZyprexaInvega
Abilify (Aripiprazole) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Risperdal (Risperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Haldol (Haloperidol) is a traditional antipsychotic. Researchers don't know exactly how it works, but it seems to change dopamine activity in your brain, which affects thoughts and mood.Seroquel (Quetiapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Zyprexa (Olanzapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Invega (Paliperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affect your thoughts and mood.
Type of medication
AbilifyRisperdalHaldolSeroquelZyprexaInvega
Antipsychotic
Atypical
Prescription only
Antipsychotic
Atypical
Prescription only
Antipsychotic
Typical
Prescription only
Antipsychotic
Atypical
Prescription only
Antipsychotic
Atypical
Prescription only
Antipsychotic
Atypical
Prescription only
Available as
AbilifyRisperdalHaldolSeroquelZyprexaInvega
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
  • Liquid
  • Injection
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
  • Injection
  • Extended release
  • Injection
Used for (click to learn more)
AbilifyRisperdalHaldolSeroquelZyprexaInvega
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Abilify (Aripiprazole)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Risperdal (Risperidone)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Haldol (Haloperidol)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Seroquel (Quetiapine)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Zyprexa (Olanzapine)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Invega (Paliperidone)
Risk factors for serious side effects
AbilifyRisperdalHaldolSeroquelZyprexaInvega
  • Elderly patients with dementia
  • Age 24 years or younger
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          • Phenylketonuria (PKU)
          Detailed Abilify (Aripiprazole) risks & warnings »
          Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
          Pregnancy category
          AbilifyRisperdalHaldolSeroquelZyprexaInvega
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
          Food
          • Abilify (Aripiprazole) can increase your blood sugar and cholesterol. However, Abilify (Aripiprazole) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
          Sleep
          • Makes you energized. Take in the morning to avoid difficulty sleeping.
          • Can cause dizziness and drowsiness.
          • It can cause dizziness, drowsiness, and can lower your blood pressure.
          • Can cause dizziness, drowsiness, and low blood pressure.
          • Can cause dizziness and drowsiness.
          • Can cause dizziness and drowsiness, or worsen you cholesterol and blood sugar levels.
          Weight
          • Least likely antipsychotic to cause weight gain.
          • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
          • Sometimes causes weight gain, sleepiness, and low blood pressure.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • More likely to cause weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Sometimes causes weight gain and low blood pressure.
          Upsides and benefits
          AbilifyRisperdalHaldolSeroquelZyprexaInvega
          • Effective at relieving psychotic symptoms and manic episodes. All antipsychotic medicines are about equally effective.
          • More energizing than other antipsychotics.
          • Fewer side effects than any other antipsychotics.
          • Least likely antipsychotic to cause weight gain.
          • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
          • Available as a generic, which is cheaper.
          • Less likely to cause heart problems compared to some antipsychotics.
          • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
          • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
          • Antipsychotic medicines are all about equally effective.
          • Less likely to cause heart problems than some antipsychotics.
          • Effective at relieving psychotic symptoms and agitation.
          • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
          • Works just as well as other antipsychotic medicines.
          • Effective at relieving psychotic symptoms and manic episodes.
          • Fewer side effects than most antipsychotic medicines.
          • Compared to other antipsychotics, the least likely to cause Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Antipsychotic medicines are all about equally effective.
          • Less likely to cause heart problems compared to some antipsychotics.
          • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
          • Lowers relapse rates for schizophrenia and bipolar disorder.
          • Antipsychotic medicines are all about equally effective.
          • Less likely to cause heart problems than some antipsychotics.
          • Effective at relieving psychotic symptoms and relapse rates for people with schizophrenia.
          • Also relieves psychotic symptoms and improves mood for people with schizoaffective disorder.
          • Less likely to cause heart or liver problems than some other antipsychotic medications.
          • Works just as well as other antipsychotic medicines.
          Downsides and risks
          AbilifyRisperdalHaldolSeroquelZyprexaInvega
          • Can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
          • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          • It's an older medicine and has a lot more side effects than newer antipsychotics.
          • Compared to other antipsychotics, it causes more hormone problems that can cause nipples to leak fluid, and sudden, dangerous abnormal heart rhythms.
          • Has a higher risk of extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements. One of these symptoms (called tardive dyskinesia) is permanent and more likely if you take this medicine for many years.
          • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
          • In studies, less effective for people over age 40 for schizophrenia.
          • Sometimes causes weight gain, sleepiness, and low blood pressure.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          • More likely to cause weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • Might make you more sleepy than some antipsychotics.
          • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          • Invega (Paliperidone) has a high risk of causing hormone problems that cause nipples to leak fluid and male breasts to grow abnormally large.
          • Sometimes causes weight gain and low blood pressure.
          • Mild risk of causing extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Not a good choice for elderly people who have dementia.
          • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
          Tips from our pharmacists for people taking the medication
          AbilifyRisperdalHaldolSeroquelZyprexaInvega
          • Makes you energized. Take in the morning to avoid difficulty sleeping.
          • May worsen cholesterol or blood sugar.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • For the first week, avoid activities that require you to be alert.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Can cause dizziness and drowsiness.
          • For the first week, avoid activities that require you to be alert.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          • It'll take 4 to 6 weeks to see the medication's full effects on your thoughts.
          • It can cause dizziness, drowsiness, and can lower your blood pressure.
          • Immediately tell your doctor if you can't control your muscle movements or if you have a fever or excess sweating.
          • Don't use in elderly people who have dementia.
          • The oral liquid concentrate can be mixed with water or juice before taking it.
          • For the first week, avoid activities like driving that require you to be alert.
          • Can cause dizziness, drowsiness, and low blood pressure.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • For the first week, avoid activities that require you to be alert.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Can cause dizziness and drowsiness.
          • For the first week, avoid activities that require you to be alert.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          • It'll take 4 to 6 weeks to see the medication's full effects on thoughts and mood.
          • Can cause dizziness and drowsiness, or worsen you cholesterol and blood sugar levels.
          • Don't worry if you see tablet shells in your stool since the medication was already absorbed by your body.
          • Elderly people who have dementia shouldn't take Invega (Paliperidone).
          • For the first week, avoid activities like driving that require you to be alert.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          Learn more
          More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
          More about RisperdalSide effectsReviews & ratingsFDA package insert
          More about HaldolSide effectsReviews & ratingsFDA package insert
          More about SeroquelSide effectsReviews & ratingsFDA package insert
          More about ZyprexaSide effectsReviews & ratingsFDA package insert
          More about InvegaSide effectsReviews & ratingsFDA package insert