Tylenol #3

(Acetaminophen / Codeine)

3.7/ 5 average rating with 581 reviewsforAcetaminophen With Codeine
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Treats mild to moderate pain.

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Prescription opioids are used to treat several kinds of pain - but they carry significant risks, including addiction. Learn more about these drugs and be sure to discuss the risks with your doctor.

Our bottom line

Tylenol #3 (Acetaminophen / Codeine) is a good option to treat pain and cough as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.

Quick facts about Acetaminophen With Codeine
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (acetaminophen / codeine)
Prices and discounts
Lowest price for 20 300mg-30mg tablets
Determining your location...
$7.50
  • Price before coupon
    $17.53
  • Lowest price with coupon
    $7.50
    57% savings

Upsides

  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relieve for mild to moderate pain to improve quality of life.
  • Good for as-needed pain and control.
  • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.

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What to expect from Acetaminophen With Codeine, on one page

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People’s experience with Acetaminophen With Codeine

581reviews so far. What do you think?

Downsides

  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Acetaminophen with codeine if you need.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • The non-opioid part of Acetaminophen with codeine, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.

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What to expect from Acetaminophen With Codeine, on one page

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Prices and discounts
Lowest price for 20 300mg-30mg tablets
Determining your location...
$7.50
  • Price before coupon
    $17.53
  • Lowest price with coupon
    $7.50
    57% savings
How it works

Tylenol #3 (Acetaminophen / Codeine) is a combination pain medicine. Codeine is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.

Quick facts about Acetaminophen With Codeine
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (acetaminophen / codeine)

Dosage forms

  • Pill
  • Liquid
People’s experience with Acetaminophen With Codeine

581reviews so far. What do you think?

What to expect when you take Tylenol #3 (Acetaminophen / Codeine) for Pain

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Side effect rates for Tylenol #3 (Acetaminophen / Codeine)

Common concerns from people taking Tylenol #3 (Acetaminophen / Codeine)

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Pregnancy
Alcohol
  • Avoid alcohol.
Food
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
  • Don't take more than instructed to prevent liver damage.
Pain
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Good for as-needed pain and control.
  • Reviewed Acetaminophen With Codeineon 4/13/2017For severe dental pain this did not work at all. Lasted maybe 30 minutes, and I could only take one every 6 hours. This pain is so unbearable I can't get out of bed. Only thing I can take while I wait for my dental surgery. I'm going to try mixing it with 600mg of ibuprofen as suggested by my dentist. I'll see if it helps at all.
    24
    Woman
    Less than a week
    Pain (mild to moderately-severe)
  • Reviewed Acetaminophen With Codeineon 8/13/2017I don't take for 3 days in a row, pain or not . Skip to avoid dependance
    65
    Woman
    Two years or more
    Pain (mild to moderately-severe)
  • Reviewed Acetaminophen / Codeineon 10/2/2017its weak and did nothing for my kidney stone pain
    40
    Man
    Less than a week
    Pain (mild to moderately-severe)
Sleep
  • Can help you fall asleep easier.
  • Dizziness and drowsiness is common, but your body may adjust.
Weight
  • Reviewed Acetaminophen With Codeineon 8/19/2017Constipation, I really have to push to urinate, as the day progresses I feel increasingly bloated and try to urinate at a time that I don't feel its needed. By the way I live in Toronto Canada and 100 pills cost $4.48
    49
    Man
    A few months
    Pain (mild to moderately-severe)