Prescription onlyLower-cost generic available



  • Pill
  • Extended release
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Treats edema, glaucoma, and seizures.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Diamox (Acetazolamide) is used to treat and prevent mountain sickness, as well as to lower the amount of fluid in the eye and legs.

  • Considered as a first choice treatment for mountain sickness.
  • Most people don't have many side effects, except for more frequent urination.
  • Available as a generic medication, so it should be reasonably priced.
  • If you're using it for swelling of the legs, it's not as good as other water pills, like hydrochlorothiazide (HCTZ).
  • If you're using Diamox (Acetazolamide) for mountain sickness, try not stay at high altitudes for too long.

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Side effects for Diamox (Acetazolamide)

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These are side effects of Diamox (Acetazolamide) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you start Diamox (Acetazolamide)

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Tips from our pharmacists
  • Don't take this with aspirin without talking to your doctor or pharmacist first.
  • Can make you tired and drowsy the first few days, so be careful driving or doing anything that requires concentration.
  • If you're using Diamox (Acetazolamide) for mountain sickness, make sure to go up in altitude very slowly.
  • Take Diamox (Acetazolamide) in the morning since you may urinate a lot the first few days.
  • Can cause numbness and tingling, temporary changes in hearing, changes in appetite, nausea, and diarrhea.

Risks and Warnings for Diamox (Acetazolamide)

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    • Higher risk if:
    • Women of childbearing age

    Diamox (Acetazolamide) has been shown to be cause birth defects. It should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Diamox (Acetazolamide)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits