Prescription onlyLower-cost generic availableClass: Gastrointestinal

Aciphex 

(rabeprazole)

Prescription onlyLower-cost generic availableClass: Gastrointestinal
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Treats heartburn and ulcers.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

No pricing data for this drug at this filter setting. Try searching onGoodRx

Upsides

  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.

Downsides

  • Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
How it works

Aciphex (Rabeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.

Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Aciphex (rabeprazole)

1153 From clinical trials of Aciphex / Gastroesophageal Reflux Disease (GERD)
  • Headache
  • Diarrhea
  • Headache
  • Nausea
  • Abdominal pain
  • Vomiting
  • Abdominal pain
  • Sore throat
  • Passing gas
  • Pain

Risks and Warnings for Aciphex (rabeprazole)

Skip risks section. Skip to common concerns section.
  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Aciphex (Rabeprazole) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Aciphex (rabeprazole)

Final section. Do you want to return to drug navigation?
Pregnancy
Interactions
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
Food
  • Take Aciphex (Rabeprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
Pain
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.