Aciphex

(Rabeprazole)

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Treats heartburn and ulcers.

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Our bottom line

Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

Quick facts about Aciphex
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (rabeprazole)
Prices and discounts
Lowest price for 30 20mg tablets
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$544.34

Upsides

  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.
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Downsides

  • Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
How it works

Aciphex (Rabeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.

Quick facts about Aciphex
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (rabeprazole)

Dosage forms

  • Extended release
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Side effect rates for Aciphex (Rabeprazole)

1153 
From clinical trials of Aciphex / Gastroesophageal Reflux Disease (GERD)
  • Headache
  • Diarrhea
  • Nausea
  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Abdominal pain
  • Pain
  • Pharyngitis

Risks and Warnings for Aciphex (Rabeprazole)

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  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Aciphex (Rabeprazole) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Aciphex (Rabeprazole)

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Pregnancy
Interactions
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
Food
  • Take Aciphex (Rabeprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
Pain
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.