Actimmune

(interferon gamma-1b)

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Helps fight some infections and slows osteoporosis.

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Our bottom line

Actimmune (interferon gamma-1b) works well to fight infections like chronic granulomatous disease and slows the progression of osteoporosis, but it is expensive.

Quick facts about Actimmune
  • Drug class: autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 20 100mg capsules
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$17.55
  • Price before coupon
    $99.28
  • Lowest price with coupon
    $17.55
    82% savings

Upsides

  • Studies show that people who take Actimmune (interferon gamma-1b) have less severe infections. They went to the hospital less often and spent less time there if they did go in.
  • Actimmune (interferon gamma-1b) can be used in infants, children, and adolescents.
  • Studies show that Actimmune (interferon gamma-1b) helps to prolong life for people with severe osteoporosis.

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What to expect from Actimmune, on one page

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Downsides

  • You'll need to be okay with getting Actimmune (interferon gamma-1b) as a shot.
  • Actimmune (interferon gamma-1b) is expensive and a generic option isn't available.
  • You'll need to get this shot 3 times a week.
  • Actimmune (interferon gamma-1b) doesn't prevent infections on its own, so you'll need to take this medicine along with another antifungal or antibacterial medication.

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Actimmune, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 20 100mg capsules
Determining your location...
$17.55
  • Price before coupon
    $99.28
  • Lowest price with coupon
    $17.55
    82% savings
How it works

Actimmune (interferon gamma-1b) is a man-made protein that's similar to your body's own natural protein. It activates your immune system to help control immune responses that have gotten out of control.

Quick facts about Actimmune
  • Drug class: autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Chronic granulomatous disease
  • Malignant osteoporosis

Dosage forms

  • Injection
Tried Actimmune? Write a review!

What to expect when you take Actimmune (interferon gamma-1b) for Chronic granulomatous disease

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Side effect rates for Actimmune (interferon gamma-1b)

From 128 clinical trials of Actimmune when taken for malignant osteoporosis/chronic granulomatous disease
  • Fever
  • Headache
  • Rash
  • Chills
  • Injection site redness or tenderness
  • Fatigue
  • Diarrhea
  • Vomiting
  • Nausea
  • Muscle pain
  • Joint pain

Risks and Warnings for Actimmune (interferon gamma-1b)

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    • Higher risk if:
    • Heart problems

    Actimmune (interferon gamma-1b) at high doses can cause flu-like symptoms that can worsen existing heart problems. Depending on your dose, your doctor may recommend that you take Actimmune (interferon gamma-1b) at bedtime or with acetaminophen (APAP) to help prevent flu-like symptoms. Speak to your doctor right away if you experience shortness of breath, fatigue and weakness, swelling in your limbs or abdomen, irregular heartbeats, sudden weight gain, lack of appetite, or persistent coughing. These could be signs of worsening heart function.

Common concerns from people taking Actimmune (interferon gamma-1b)

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Kidneys and liver
  • Actimmune (interferon gamma-1b) can cause liver damage, especially if you have a history of liver problems or if you're taking other medicines that can affect your liver. Your doctor may request regular lab tests to check your liver function. Let your doctor know right away if you experience appetite/weight loss, stomach discomfort, vomiting, dark urine, yellowing of skin/eyes, or changes in stool color.
  • People with kidney problems may have a hard time getting rid of Actimmune (interferon gamma-1b) from your body. This can cause Actimmune (interferon gamma-1b) to build up and increase your risk of getting side effects. Let your doctor know if you have a history of kidney problems. You may need to get regular lab tests done to monitor your kidney function.
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.