Prescription onlyClass: Neuro/psych



Prescription onlyClass: Neuro/psych
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Calms sudden changes in behavior in people with mental illness.

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Our bottom line

Adasuve (loxapine) is only used when a person with schizophrenia or bipolar disorder is suddenly having inappropriate behavior or feelings even though they are taking their regular medicines. Your loved one has to live in a place that's watched over by doctors or nurses, since they're the only ones who can give Adasuve (loxapine).


  • Adasuve (loxapine) works faster and lasts longer to calm people down versus other medicines.
  • Adasuve (loxapine) is the only medicine in its class that's inhaled in case people aren't able to swallow pills or take injections.
  • Because only a doctor or nurse can give Adasuve (loxapine), they can figure out right away if it's working for your loved one, and help them if they have trouble breathing.
  • Adasuve (loxapine) is one of the few medicines in its class that doesn't affect the heartbeat.


  • Adasuve (loxapine) can only be given by a doctor or nurse, and your loved one has to be calm enough to use an inhaler.
  • Adasuve (loxapine) is not widely available because additional training and certification are required before it can be given.
  • Adasuve (loxapine) cannot be used more than once every 24 hours because of it can hurt the lungs."
How it works

Adasuve (loxapine) is a typical antipsychotic. Researchers aren't exactly clear how Adasuve (loxapine) works to calm someone down. It adjusts levels of dopamine and serotonin in the brain, two chemicals known to regulate mood.

What to expect when you take Adasuve (loxapine) for Schizophrenia or bipolar disorder

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Side effect rates for Adasuve (loxapine)

522 From clinical trials of Adasuve / Schizophrenia or bipolar disorder
  • Changes in taste
  • Sleepiness
  • Throat irritation

Risks and Warnings for Adasuve (loxapine)

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    • Higher risk if:
    • COPD
    • Asthma

    Because Adasuve (loxapine) can cause problems with breathing, people with asthma or COPD shouldn't take it. The doctor will make sure your loved one doesn't have these problems, and the facility they live in is specially trained to give it.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Adasuve (loxapine)

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