Adempas

(riociguat)

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Treats high blood pressure in the lungs.

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Our bottom line

One of the few pills you can take to treat high blood pressure in the lungs, but it can be expensive.

Quick facts about Adempas
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Improves your ability to exercise.
  • Less likely to have bad side effects compared to other medicines.

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Downsides

  • Women must go through a special program to get Adempas (riociguat) because it can cause birth defects.
  • You can't take Adempas (riociguat) with nitrates like nitroglycerin (Nitrostat) or PDE-5 inhibitors like sildenafil because it can lower your blood pressure too much.
  • Not available in generic, so it can be very expensive.
  • You have to take Adempas (riociguat) three times a day, and your doctor might have to change the dose frequently.

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What to expect from Adempas, on one page

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How it works

Adempas (riociguat) relaxes blood vessels in the lungs which lowers blood pressure.

Quick facts about Adempas
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Pulmonary arterial hypertension
  • Chronic thromboembolic pulmonary hypertension

Dosage forms

  • Pill
Tried Adempas? Write a review!

What to expect when you take Adempas (riociguat) for Pulmonary arterial hypertension

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Side effect rates for Adempas (riociguat)

From 704 clinical trials of Adempas when taken for cteph and pah
  • Headache
  • Indigestion and stomach pain
  • Dizziness
  • Nausea
  • Diarrhea
  • Low blood pressure
  • Vomiting
  • Low red blood cell count
  • Gastroesophageal reflux disease
  • Constipation

Risks and Warnings for Adempas (riociguat)

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    • Higher risk if:
    • Pregnancy

    Women who are able to get pregnant must enroll in a special monitoring program before they can take Adempas (riociguat). Adempas (riociguat) causes birth defects, and women must take regular pregnancy tests and be on birth control while taking it.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect