Prescription onlyClass: Respiratory

Advair Diskus 

(fluticasone / salmeterol)

Prescription onlyClass: Respiratory
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Prevents breathing problems.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Advair Diskus (Fluticasone / Salmeterol) is good for people who need two medicines to control their asthma or COPD, but it might be expensive since there's no generic available.

Price and discounts
Best available price for 1 (0.45g of 113mcg/14mcg) respiclick inhaler of fluticasone / salmeterol


  • 2-in-1 medicine that lowers inflammation and opens airways in your lungs. Medicines are more effective together than alone.
  • Makes lung function significantly better.
  • Lowers the number of flare-ups and rescue inhaler uses in asthma and COPD.
  • You only have to use it twice a day.
  • Both the Diskus and inhaler can be used to treat asthma.
People say this drug is:
799 reviews


  • You have to use Advair every day to control your symptoms.
  • You can't lower the dose or stop taking it too suddenly.
  • The HFA inhaler isn't approved to treat COPD.
  • Can make your heart race.
  • Steroids can slow height growth in kids.
  • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
  • There have been some reports of worsening asthma leading to death when taking this medicine.
How it works

Advair Diskus (Fluticasone / Salmeterol) is a combination medicine. Fluticasone (a corticosteroid) lowers lung inflammation to control asthma and COPD. Salmeterol (a bronchodilator) relaxes muscles in your lungs to open airways and make breathing easier.

What to expect when you take Advair Diskus (fluticasone / salmeterol) for Asthma

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Advair Diskus (fluticasone / salmeterol)

Risks and Warnings for Advair Diskus (fluticasone / salmeterol)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.

    There are reports of worsening asthma leading to death in people taking Advair Diskus (Fluticasone / Salmeterol). It is related to one of the medications in this product. Advair Diskus (Fluticasone / Salmeterol) should only be used if your symptoms have not improved with a fast-acting or controller medication alone. If this happens, call 911 or your doctor right away.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Advair Diskus (fluticasone / salmeterol)

Final section. Do you want to return to drug navigation?
Kidneys and liver
  • Adrenal suppression can occur if you lower your dose or stop taking Advair Diskus (Fluticasone / Salmeterol) too quickly which is related to one of the medications in the combination. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your medication need to be done slowly and over time. Talk to your doctor before you decrease or stop Advair Diskus (Fluticasone / Salmeterol).
  • Steroids can slow height growth in kids.