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Advil Allergy Sinus Alternatives

(Ibuprofen / Pseudoephedrine / Chlorpheniramine)

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Compare Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) to alternatives

These medications are comparable to Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) or used for similar purposes.

Advil Allergy Sinus
(Ibuprofen / Pseudoephedrine / Chlorpheniramine)

Zyrtec D
(Cetirizine / Pseudoephedrine)

Sudafed
(Pseudoephedrine)

Claritin D
(Loratadine / Pseudoephedrine)

Allegra D
(Pseudoephedrine / Fexofenadine)

Advil Allergy And Congestion Relief
(Chlorpheniramine / Ibuprofen / Phenylephrine)

Benadryl
(Diphenhydramine)

Sudafed Pe
(Phenylephrine)

Nyquil Cold And Flu
(Acetaminophen / Dextromethorphan / Doxylamine)

Alka-Seltzer Plus Night Cold And Flu
(Acetaminophen / Doxylamine / Dextromethorphan / Phenylephrine)

Relieves cold and allergy symptoms. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) is good for multiple allergy and cold symptoms, but check to be sure you really need all of its ingredients.Relieves congestion and allergy symptoms. Zyrtec D (Cetirizine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Treats allergy symptoms and congestion. Allegra D (Pseudoephedrine / Fexofenadine) is a combination allergy medicine that's useful if you have congestion and runny nose.Relieves cold and allergy symptoms. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is an okay combination medicine to relieve pain and congestion. The antihistamine can make you sleepy and the decongestant can keep you awake, so it could affect you either way.Treats allergy symptoms and helps you sleep. Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.Clears your sinuses. Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects.Relieves cold and flu symptoms, and helps you sleep. Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a useful combination medicine that relieves cold and flu symptoms and will help you sleep. Make sure you really need all of its ingredients.Relieves cold and flu symptoms, and helps you sleep. Alka-Seltzer Plus Night Cold And Flu (Acetaminophen / Doxylamine / Dextromethorphan / Phenylephrine) is good for multiple cold symptoms at night, but it's more medicine than you need if you only have one symptom.
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Reviews & ratings
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4.9423226812159005Advil Allergy Sinus
Reviews for Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
71%
of people say Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) is worth it
35%
say it works well
7%
say it's a big hassle
Reviews for Zyrtec D (Cetirizine / Pseudoephedrine)
75%
+4% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
43%
+8% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
9%
2% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
Reviews for Sudafed (Pseudoephedrine)
82%
+11% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
45%
+10% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
6%
+1% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
Reviews for Claritin D (Loratadine / Pseudoephedrine)
69%
2% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
38%
+3% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
8%
1% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
73%
+2% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
30%
5% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
6%
+1% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
Reviews for Benadryl (Diphenhydramine)
85%
+14% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
57%
+22% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
8%
1% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
Reviews for Sudafed Pe (Phenylephrine)
44%
27% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
23%
12% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
10%
3% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
Reviews for Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine)
83%
+12% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
42%
+7% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)
6%
+1% vs. Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine)

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Side effects
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu

We haven’t found good data for Advil Allergy Sinus side effects.

FDA side effect reports for Advil Allergy Sinus »

We haven’t found good data for Zyrtec D side effects.

FDA side effect reports for Zyrtec D »

We haven’t found good data for Sudafed side effects.

FDA side effect reports for Sudafed »

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »
  • Back pain 2%
More Allegra D side effects »

We haven’t found good data for Advil Allergy and Congestion Relief side effects.

FDA side effect reports for Advil Allergy and Congestion Relief »

We haven’t found good data for Benadryl side effects.

FDA side effect reports for Benadryl »

We haven’t found good data for Phenylephrine side effects.

FDA side effect reports for Phenylephrine »

We haven’t found good data for Nyquil Cold and Flu side effects.

FDA side effect reports for Nyquil Cold and Flu »

We haven’t found good data for Alka-Seltzer Plus Night Cold and Flu side effects.

FDA side effect reports for Alka-Seltzer Plus Night Cold and Flu »
How it works
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) is a combination medicine to treat allergy and cold symptoms. Ibuprofen (an NSAID) relieves swelling, pain, and fever. Pseudoephedrine (a decongestant) clears your sinuses. Chlorpheniramine (an antihistamine) treats nasal allergy symptoms.Zyrtec D (Cetirizine / Pseudoephedrine) is a combination medicine for allergies. Cetirizine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Sudafed (Pseudoephedrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Allegra D (Pseudoephedrine / Fexofenadine) is a combination medicine that relieves allergy symptoms. Fexofenadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itching. Pseudoephedrine (a decongestant) clears your sinuses.Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Phenylephrine is a decongestant that clears your sinuses.Benadryl (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.Sudafed Pe (Phenylephrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Doxylamine is an antihistamine that relieves a runny nose and makes you very sleepy.Alka-Seltzer Plus Night Cold And Flu (Acetaminophen / Doxylamine / Dextromethorphan / Phenylephrine) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses. Doxylamine is an antihistamine that relieves a runny nose and makes you very sleepy.
Type of medication
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
Pain reliever
NSAID
DecongestantAntihistamine
1st generation
Over-the-counter
Antihistamine
2nd generation
DecongestantPrescription or OTC
DecongestantPrescription or OTC
Antihistamine
2nd generation
DecongestantPrescription or OTC
DecongestantAntihistamine
2nd generation
Prescription or OTC
Antihistamine
1st generation
Pain reliever
NSAID
DecongestantOver-the-counter
Antihistamine
1st generation
Prescription or OTC
DecongestantPrescription or OTC
Pain reliever
APAP
Cough suppressantAntihistamine
Ethanolamine derivative
Over-the-counter
Pain reliever
Acetaminophen (APAP)
Antihistamine
Ethanolamine derivative
Cough suppressantDecongestantOver-the-counter
Available as
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Liquid
  • Extended release
  • Extended release
  • Pill
  • Pill
  • Oral solution
  • Cream, gel, or ointment
  • Pill
  • Nasal spray
  • Eye drops
  • Suppository
  • Pill
  • Liquid
  • Pill
Used for (click to learn more)
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
Risk factors for serious side effects
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Women of childbearing age
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) risks & warnings »
Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
Pregnancy category
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
  • Don't take it with alcohol or other drugs that make you sleepy.
No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Don't take it with alcohol or other drugs that make you sleepy.
No specific alcohol-related info.
  • Avoid using alcohol and other drugs that make you drowsy.
No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
Kidneys and liver
  • Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) for any amount of time.
No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.
  • The antihistamine (Cetirizine) can cause more drowsiness than similar antihistamines, like Allegra D (which contains Fexofenadine) and Claritin D (which contains Loratadine).
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • The antihistamine (Cetirizine) in Zyrtec D (Cetirizine / Pseudoephedrine) causes less drowsiness than other medications like Benadryl.
  • It's better to take Zyrtec D (Cetirizine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • It can affect the quality of your sleep, so you can't take it too close to going to bed.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
  • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • Shouldn't use it before you want to sleep.
  • The antihistamine (doxylamine) will help you sleep.
  • Avoid using alcohol and other drugs that make you drowsy.
  • The antihistamine (doxylamine) can help you sleep.
Weight
No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
Upsides and benefits
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
  • Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) is a combination medicine that relieves allergy and cold symptoms. It's good to use if you have a runny nose, watery eyes, sneezing, headache, congestion, sore throat, or fever.
  • Ibuprofen (a pain reliever) is more effective than acetaminophen at lowering fever and relieving sinus pain.
  • Chlorpheniramine makes you less tired than other antihistamines.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
  • The antihistamine (Cetirizine) in Zyrtec D (Cetirizine / Pseudoephedrine) causes less drowsiness than other medications like Benadryl.
  • The decongestant (Pseudoephedrine) in Zyrtec D (Cetirizine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
  • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
  • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
  • It's available without a prescription, unlike other strong allergy medicines.
  • One of the best over-the-counter options to clear stuffy nose and help you breathe better.
  • Clears nasal congestion better than other decongestants like phenylephrine.
  • Can be helpful in relieving congestion-related headaches and pressure in your ears.
  • Available in regular and extended release forms.
  • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
  • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
  • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
  • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
  • It's available without a prescription, unlike other strong allergy medicines.
  • Available without a prescription in the drugstore.
  • It has two medications that work in different ways to help relieve nasal symptoms.
  • The antihistamine (fexofenadine) is useful for relieving itchy eyes, runny nose, or constant sneezing.
  • The decongestant (pseudoephedrine) is very good at relieving congestion.
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
  • Works to clear nasal congestion and helps you breathe better.
  • Helpful in relieving congestion-related headaches.
  • Has fewer side effects than other decongestants like pseudoephedrine.
  • It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Doesn't give you rebound congestion (worse symptoms when you stop taking it) like nasal spray decongestants do.
  • Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have watery eyes, a cough, fever, and pain.
  • The cough medicine (dextromethorphan) works well and has very few side effects.
  • The antihistamine (doxylamine) will help you sleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • Alka-Seltzer Plus Night Cold And Flu (Acetaminophen / Doxylamine / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The cough suppressant (dextromethorphan) works well and has very few side effects.
  • The antihistamine (doxylamine) can help you sleep.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
Downsides and risks
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
  • If you don't really need all of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine, the decongestant in Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine), can make your heart race or make you feel anxious and restless.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • The antihistamine (Cetirizine) can cause more drowsiness than similar antihistamines, like Allegra D (which contains Fexofenadine) and Claritin D (which contains Loratadine).
  • You can have more side effects when using combination pills than when using single-ingredient medications.
  • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
  • Pseudoephedrine (a decongestant) can make your heart race or make you feel anxious and restless.
  • It can affect the quality of your sleep, so you can't take it too close to going to bed.
  • Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions.
  • Sudafed (Pseudoephedrine) isn't as effective after using it for more than 4 days straight.
  • Need to show a photo ID to buy it in the drugstore and there is a limit on how much you can buy each visit.
  • You can have more side effects when using combination pills than when using single-ingredient medications.
  • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
  • Has more side effects than Allegra since it has pseudoephedrine in it.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • You must show a photo ID to buy this from behind the pharmacy counter. There's a maximum limit on how much you can buy in the pharmacy at a time.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed).
  • Can make your heart race or make you feel anxious and restless.
  • Shouldn't use it before you want to sleep.
  • Not as effective after using it for 4 days in a row.
  • You shouldn't use it if you have high blood pressure.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Tips from our pharmacists for people taking the medication
Advil Allergy SinusZyrtec DSudafedClaritin DAllegra DAdvil Allergy and Congestion ReliefBenadrylPhenylephrineNyquil Cold and FluAlka-Seltzer Plus Night Cold and Flu
  • You need to show an ID to buy Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) in the drugstore because it contains pseudoephedrine.
  • Take it after eating to avoid getting an upset stomach.
  • Be careful taking Advil Allergy Sinus (Ibuprofen / Pseudoephedrine / Chlorpheniramine) if you have a history of bleeding problems or ulcers since it can make them worse.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • You need to show an ID to buy Zyrtec D (Cetirizine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
  • It's better to take Zyrtec D (Cetirizine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • Starts working in 30 minutes.
  • Don't cut, crush, or chew tablets; swallow them whole.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
  • You need to show an ID to buy Sudafed (Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Don't take Sudafed (Pseudoephedrine) too close to bedtime since it can keep you awake.
  • Talk to your doctor if your symptoms don't get better in 1 week.
  • Starts working in 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
  • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • Starts working in 30 minutes.
  • Don't cut, crush, or chew tablets; swallow them whole.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
  • It works best if you have nasal congestion and a runny nose.
  • Take on an empty stomach, 1 hour before eating or 2 hours after eating.
  • Shouldn't be used in kids younger than 12 years old.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
  • Can cause dizziness, headache, or a fast heartbeat.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Chlorpheniramine (the antihistamine ingredient in Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Don't use in kids age 12 years or younger.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Take it as needed every 4 to 6 hours.
  • Benadryl (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
  • If you only have itchy or watery eyes, try using just an antihistamine eye drop.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • Phenylephrine can make you restless, so don't take it too close to bedtime.
  • It's in other cold and flu combination medicines. Read labels closely so you don't accidentally double up and take too much of it in a day.
  • Follow age-specific dosing instructions on how much to take.
  • Starts working in 30 minutes.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Avoid using alcohol and other drugs that make you drowsy.
  • Doxylamine (the antihistamine ingredient) can make you tired, so take it close to bedtime.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
  • Alka-Seltzer Plus Night Cold And Flu (Acetaminophen / Doxylamine / Dextromethorphan / Phenylephrine) starts working in about 30 minutes.
  • Doxylamine (the antihistamine ingredient) can make you tired, so take it close to bedtime.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
Learn more
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