Over-the-counterLower-cost generic available

Advil Pm

(Diphenhydramine / Ibuprofen)

  • Pill
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Relieves pain and helps you sleep.

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Over-the-counterLower-cost generic available

Our pharmacists’ bottom line

Advil Pm (Diphenhydramine / Ibuprofen) works well at relieving pain and also helps you sleep.

  • Advil Pm (Diphenhydramine / Ibuprofen) works well when you have a cold or the flu, but can also be used for backaches, minor arthritis, and joint pain.
  • Can be used for anyone 12 years or older.
  • Isn't habit-forming like some other pain medicines and sleep aids.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • The antihistamine (diphenhydramine) can make you feel groggy the next morning.
  • Can only take one dose in 24 hours.
  • Can increase the risk of falls, so elderly people shouldn't use it.

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Side effects for Advil Pm (Diphenhydramine / Ibuprofen)

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These are side effects of Advil Pm (Diphenhydramine / Ibuprofen) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Advil Pm (Diphenhydramine / Ibuprofen)

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Tips from our pharmacists
  • Contains ibuprofen, so take it with food to avoid stomach problems and ulcers.
  • Diphenhydramine makes you tired, so take Advil Pm (Diphenhydramine / Ibuprofen) before you go to sleep.
  • Don't take Advil Pm (Diphenhydramine / Ibuprofen) with alcohol or other drugs that make you sleepy.
  • Don't take Advil Pm (Diphenhydramine / Ibuprofen) if you're pregnant.

Risks and Warnings for Advil Pm (Diphenhydramine / Ibuprofen)

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    • Higher risk if:
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day

    Advil Pm (Diphenhydramine / Ibuprofen) contains aspirin, which can cause serious problems including inflammation, bleeding, and ulcers in the stomach or intestines. The longer you take Advil Pm (Diphenhydramine / Ibuprofen), the higher the risk is. If you notice blood or a dark/black color in your stool, tell your doctor right away.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Advil Pm (Diphenhydramine / Ibuprofen)

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The FDA category for this medication is N. It is advised that you: Unknown
Pregnancy
Alcohol
  • Tips from our pharmacists
  • Don't take Advil Pm (Diphenhydramine / Ibuprofen) with alcohol or other drugs that make you sleepy.
Food
  • Tips from our pharmacists
  • Contains ibuprofen, so take it with food to avoid stomach problems and ulcers.
Sleep
  • Upsides and downsides from our pharmacists
  • Isn't habit-forming like some other pain medicines and sleep aids.
  • Tips from our pharmacists
  • Diphenhydramine makes you tired, so take Advil Pm (Diphenhydramine / Ibuprofen) before you go to sleep.
  • Risks from our pharmacists
  • Diphenhydramine, also known as Benadryl, is an antihistamine in Advil Pm (Diphenhydramine / Ibuprofen) that can make you feel dizzy or drowsy. People who are at a higher risk of falls should avoid using Advil Pm (Diphenhydramine / Ibuprofen).