Clears your sinuses.
Our bottom line
Afrin (Oxymetazoline) clears stuffy noses well, but don't use it for more than 3 days in a row or your congestion could get worse.
- It works right away and each dose provides relief for up to 12 hours.
- Can use for nasal congestion caused by colds and allergies.
- It only affects your nose, so there aren't too many other side effects.
- Available as a nasal spray and a nasal mist.
- Afrin (Oxymetazoline), like all other sprays used for stuffy noses, can make your congestion worse if you use it for more than 3 or 4 days in a row (called rebound-congestion).
- Can cause temporary stinging, burning, or dryness in your nose.
- Can't be used for kids younger than 6 years old.
Afrin (Oxymetazoline) is a nasal decongestant. It reduces swelling in your nose to make breathing easier.
- Nasal spray
Side effect rates for Afrin (oxymetazoline)
Risks and Warnings for Afrin (oxymetazoline)Skip risks section. Skip to common concerns section.
- Higher risk if:
- › Using Afrin (Oxymetazoline) for more than 3 days
Don't use it for more than 3 days in a row. Continuing to use Afrin (Oxymetazoline) for longer may cause “rebound” congestion once you stop using it, meaning your congestion could come back again, just as bad or even worse. It's best to slowly lower the amount you use over a few days and use a non-medicated nasal spray, like saline (salt-water), to clear up stuffiness.