Prescription onlyLower-cost generic availableClass: Cardiovascular

Aggrenox Alternatives

(aspirin / dipyridamole)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Aggrenox (aspirin / dipyridamole) to alternatives

These medications are comparable to Aggrenox (aspirin / dipyridamole) or used for similar purposes.

Aggrenox
(aspirin / dipyridamole)

Plavix
(clopidogrel)

aspirin

Ticlid
(ticlopidine)

Pletal
(cilostazol)

Prevents blood clots that can cause a stroke. Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.Prevents blood clots. Plavix (Clopidogrel) works well to prevent blood clots and heart complications, but watch out for drug interactions.Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.Coming soon.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Aggrenox (aspirin / dipyridamole)
Not enough review data. Review it!
of people (All ages) say Aggrenox (aspirin / dipyridamole) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Aggrenox (aspirin / dipyridamole)?
Worth itNot sureNot worth it
Reviews for Plavix (clopidogrel)
59%
+9% better vs. Aggrenox (aspirin / dipyridamole)
49%
-51% worse vs. Aggrenox (aspirin / dipyridamole)
16%
-16% worse vs. Aggrenox (aspirin / dipyridamole)
343 reviews
Have you used Plavix (clopidogrel)?
Worth itNot sureNot worth it
Reviews for Aspirin
76%
+26% better vs. Aggrenox (aspirin / dipyridamole)
41%
-59% worse vs. Aggrenox (aspirin / dipyridamole)
6%
-6% worse vs. Aggrenox (aspirin / dipyridamole)
533 reviews
Have you used Aspirin?
Worth itNot sureNot worth it
Reviews for Ticlid (ticlopidine)
Not enough review data. Review it!
-50% worse vs. Aggrenox (aspirin / dipyridamole)
Not enough review data. Review it!
-100% worse vs. Aggrenox (aspirin / dipyridamole)
Not enough review data. Review it!
Same vs. Aggrenox (aspirin / dipyridamole)
Have you used Ticlid (ticlopidine)?
Worth itNot sureNot worth it
Reviews for Pletal (cilostazol)
Not enough review data. Review it!
-50% worse vs. Aggrenox (aspirin / dipyridamole)
Not enough review data. Review it!
-100% worse vs. Aggrenox (aspirin / dipyridamole)
Not enough review data. Review it!
Same vs. Aggrenox (aspirin / dipyridamole)
Have you used Pletal (cilostazol)?
Worth itNot sureNot worth it
Side effects
AggrenoxPlavixAspirinTiclidPletal
  • Headache 10%
  • Indigestion 3%
  • Abdominal pain 6%
  • Nausea 6%
  • Diarrhea 3%
  • Vomiting 1%
  • Joint pain 1%
More Aggrenox side effects »
  • Minor bleeding 3%
  • Major bleeding 1%
  • Any noncerebral bleeding 1%
More Plavix side effects »

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »

We haven’t found good data for Ticlid side effects.

FDA side effect reports for Ticlid »

We haven’t found good data for Pletal side effects.

FDA side effect reports for Pletal »
How it works
AggrenoxPlavixAspirinTiclidPletal
Aggrenox (Aspirin / Dipyridamole) is an antiplatelet blood thinner. It is a combination medication with two ingredients, aspirin and dipyridamole. Both make it harder for your body to form blood clots.Plavix (Clopidogrel) is an antiplatelet blood thinner. It prevents blood platelets from working, which makes it harder for your body to form blood clots.Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.Coming soon.Coming soon.
Type of medication
AggrenoxPlavixAspirinTiclidPletal
Prescription only
Prescription only
Over-the-counter
Available as
AggrenoxPlavixAspirinTiclidPletal
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
Used for
AggrenoxPlavixAspirinTiclidPletal
  • Placement Of Stent In Coronary Artery Adjunct Thromboembolic Stroke
  • Intermittent Claudication
Risk factors for serious side effects
AggrenoxPlavixAspirinTiclidPletal
  • Children 18 years or younger recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 or older
  • Also taking other blood thinners
  • Drinking 3 or more alcoholic drinks a day
Detailed Aggrenox (aspirin / dipyridamole) risks & warnings »
  • Genetic variation (CYP2C19 poor metabolizer)
  • Drug-interactions
  • Age greater than 65
  • History of gastrointestinal bleeding
  • High blood pressure
Detailed Plavix (clopidogrel) risks & warnings »
  • Children 18 years or younger
  • Children recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking Aspirin, NSAIDs, or blood thinners
Detailed Aspirin risks & warnings »
    Coming soon.
      Coming soon.
      Pregnancy

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      AggrenoxPlavixAspirinTiclidPletal
      No interactions related info.
      • Lots of interactions with other drugs or supplements. Always check with your doctor or pharmacist before starting any new meds.
      • Interacts with a lot of medicines and supplements. Don't start any new meds without talking to your doctor.
      No interactions related info.No interactions related info.No interactions related info.
      Food
      AggrenoxPlavixAspirinTiclidPletal
      • Do not crush or chew capsules. Can take with or without food.
      No food related info.
      • Take with food to lower the chance of an upset stomach.
      No food related info.No food related info.
      Kidneys and liver
      AggrenoxPlavixAspirinTiclidPletal
      • Do not use Aggrenox (Aspirin / Dipyridamole) if you have severe kidney disease.
      No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
      Pain
      AggrenoxPlavixAspirinTiclidPletal
      No pain related info.No pain related info.
      • Used in higher doses to relieve pain, swelling, and fever.
      No pain related info.No pain related info.
      Upsides and benefits
      AggrenoxPlavixAspirinTiclidPletal
      • This helps to prevent strokes for people who had a stroke or TIA (transient ischemic attack) before.
      • In clinical studies, Aggrenox (Aspirin / Dipyridamole) lowered the chance of another stroke for a person with a previous stroke or mini-stroke (TIA) by 36%.
      • Works better than either aspirin or dipyridamole alone to prevent strokes.
      • Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke.
      • Thins your blood to protect your heart after a heart attack or after a procedure on your heart.
      • Studies have shown clopidogrel lowers your risk of death or further heart complications.
      • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
      • Used in higher doses to relieve pain, swelling, and fever.
      • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
      Coming soonComing soon
      Downsides and risks
      AggrenoxPlavixAspirinTiclidPletal
      • Raises your risk for bleeding and bruising.
      • Has to be taken twice a day unlike Plavix that only has to be taken once daily.
      • Can be more expensive than other alternatives that are available as a generic.
      • Can't be used by people with an aspirin allergy, or a history of stomach ulcers.
      • Raises your risk of bleeding and bruising.
      • Lots of interactions with other drugs or supplements. Always check with your doctor or pharmacist before starting any new meds.
      • Doesn't work well for people with certain genetic variations.
      • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
      • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
      • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
      • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
      Coming soonComing soon
      Tips from our pharmacists for people taking the medication
      AggrenoxPlavixAspirinTiclidPletal
      • Take twice daily.
      • Do not crush or chew capsules. Can take with or without food.
      • Aggrenox (Aspirin / Dipyridamole) can cause unexpected bleeding or bruising.
      • Don't take if you're allergic to aspirin.
      • Headache is a common side effect, but it often goes away after the first week of use.
      • Thins your blood to prevent clots from forming or getting bigger. Doesn't break up existing clots.
      • Can raise your risk of bleeding or bruising.
      • Take it exactly as instructed.
      • Interacts with a lot of medicines and supplements. Don't start any new meds without talking to your doctor.
      • Let your doctor know about any fever, weakness, or unusual bleeding or bruising.
      • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
      • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
      • Take with food to lower the chance of an upset stomach.
      • Don't use for kids younger than 18 years old.
      • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
      Coming soonComing soon
      Learn more
      More about AggrenoxSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Aggrenox (aspirin / dipyridamole)?
      Worth itNot sureNot worth it
      More about PlavixSide effectsReviews & ratingsFDA package insert
      Have you used Plavix (clopidogrel)?
      Worth itNot sureNot worth it
      More about AspirinSide effectsReviews & ratingsFDA package insert
      Have you used Aspirin?
      Worth itNot sureNot worth it
      More about TiclidSide effectsFDA package insert
      Have you used Ticlid (ticlopidine)?
      Worth itNot sureNot worth it
      More about PletalSide effectsFDA package insert
      Have you used Pletal (cilostazol)?
      Worth itNot sureNot worth it