Prescription onlyLower-cost generic available

Aldactazide

(Spironolactone / Hydrochlorothiazide)

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Lowers blood pressure. Removes extra water from your body.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Aldactazide (Spironolactone / Hydrochlorothiazide) removes excess fluid in your body and lowers your blood pressure, while helping keep your potassium levels safe.

  • Lowers the risk of heart attack and stroke.
  • Has a low risk of causing muscle problems due to low potassium levels in your blood.
  • Gets rid of extra fluids in your body.
  • Helpful for people who tend to have low potassium levels.
  • Many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • Needs blood tests to monitor electrolytes and kidney function.
  • Can make you urinate more often.
  • Can make you sensitive to sunlight.
  • Shouldn't take it if you have a sulfa allergy.

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Side effects for Aldactazide (Spironolactone / Hydrochlorothiazide)

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These are side effects of Aldactazide (Spironolactone / Hydrochlorothiazide) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Aldactazide (Spironolactone / Hydrochlorothiazide)

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Tips from our pharmacists
  • Makes you urinate more often, so don't take it at bedtime.
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how it affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Tell your doctor about any dizziness, muscle weakness, skin changes, red or black tarry stool.
  • Can make your skin more sensitive to sun, so use proper protections.

Risks and Warnings for Aldactazide (Spironolactone / Hydrochlorothiazide)

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  • Use of Aldactazide (Spironolactone / Hydrochlorothiazide) in rats showed higher risk of tumor growth, and should only be used for FDA approved indications.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Aldactazide (Spironolactone / Hydrochlorothiazide)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
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Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Needs blood tests to monitor electrolytes and kidney function.
  • Tips from our pharmacists
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Risks from our pharmacists
  • Aldactazide (Spironolactone / Hydrochlorothiazide) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
  • Aldactazide (Spironolactone / Hydrochlorothiazide) can affect levels of certain electrolytes (sodium, magnesium) that can cause muscle weakness/spasms or unexplained tiredness. Baseline and routine blood tests are needed to monitor your electrolytes and kidney function.