Prescription onlyLower-cost generic availableClass: Cardiovascular

Aldactazide Alternatives

(Spironolactone / Hydrochlorothiazide)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Aldactazide (Spironolactone / Hydrochlorothiazide) to alternatives

These medications are comparable to Aldactazide (Spironolactone / Hydrochlorothiazide) or used for similar purposes.

Aldactazide
(Spironolactone / Hydrochlorothiazide)

Midamor
(Amiloride)

Microzide
(Hydrochlorothiazide )

Dyazide
(Hydrochlorothiazide / Triamterene)

Aldactone
(spironolactone)

Dyrenium
(Triamterene)

Inspra
(Eplerenone)

Lowers blood pressure. Removes extra water from your body. Aldactazide (Spironolactone / Hydrochlorothiazide) removes excess fluid in your body and lowers your blood pressure, while helping keep your potassium levels safe.Coming soon.Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.Coming soon.
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Reviews & ratings
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Aldactazide (Spironolactone / Hydrochlorothiazide)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Midamor (Amiloride)?
Worth itNot sureNot worth it
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
+47% better vs. Aldactazide (Spironolactone / Hydrochlorothiazide)
31%
+31% better vs. Aldactazide (Spironolactone / Hydrochlorothiazide)
16%
-16% worse vs. Aldactazide (Spironolactone / Hydrochlorothiazide)
139 reviews
Have you used Microzide (Hydrochlorothiazide (Hctz))?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Dyazide (Hydrochlorothiazide / Triamterene)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Dyrenium (Triamterene)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Inspra (Eplerenone)?
Worth itNot sureNot worth it
Side effects
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra

We haven’t found good data for Aldactazide side effects.

FDA side effect reports for Aldactazide »

We haven’t found good data for Amiloride side effects.

FDA side effect reports for Amiloride »

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

We haven’t found good data for Dyazide side effects.

FDA side effect reports for Dyazide »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Triamterene side effects.

FDA side effect reports for Triamterene »

We haven’t found good data for Inspra side effects.

FDA side effect reports for Inspra »
How it works
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
Aldactazide (Spironolactone / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure with two diuretics (water pills), hydrochlorothiazide and spironolactone. They act on different parts of your kidney to get rid of extra fluids.Coming soon.Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Coming soon.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Coming soon.
Type of medication
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
Prescription only
Prescription only
Prescription only
Available as
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
Used for
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
  • Congestive Heart Failure Hypertension
  • Edema Hypertension
  • Edema
  • Heart Failure Myocardial Infarction With Complication Hypertension
Risk factors for serious side effects
AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    • Current kidney problems
    • Medicine that affects electrolytes
    • History of sulfa allergies
    • Taking with alcohol
    • Taking other medicines that make you less alert
      Detailed Aldactazide (Spironolactone / Hydrochlorothiazide) risks & warnings »
      Coming soon.
      • Current electrolyte imbalance
      • History of sulfa allergies
      • History of gout
      • Current kidney problems
        Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
        Coming soon.
          • Taking with alcohol
          • Taking other medicines that lower your blood pressure
          • Current kidney problems
          • Taking other medicines that increase potassium
          • Use of salt substitutes
            Detailed Aldactone (spironolactone) risks & warnings »
            Coming soon.Coming soon.
            Pregnancy

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            Kidneys and liver
            AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
            • Needs blood tests to monitor electrolytes and kidney function.
            • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
            • Aldactazide (Spironolactone / Hydrochlorothiazide) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
            No kidneys and liver related info.
            • Requires routine blood tests to check kidney function.
            No kidneys and liver related info.
            • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
            No kidneys and liver related info.No kidneys and liver related info.
            Pain
            AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
            No pain related info.No pain related info.No pain related info.No pain related info.
            • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
            No pain related info.No pain related info.
            Upsides and benefits
            AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
            • Lowers the risk of heart attack and stroke.
            • Has a low risk of causing muscle problems due to low potassium levels in your blood.
            • Gets rid of extra fluids in your body.
            • Helpful for people who tend to have low potassium levels.
            Coming soon
            • Works well to get rid of extra fluids in your body through urination.
            • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
            • Lowers the risk of heart attack and stroke.
            • Good option if you have both high blood pressure and heart failure.
            • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
            • Most people have very few side effects.
            Coming soon
            • Has a low risk of causing muscle problems from low potassium levels in your blood.
            • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
            • Can lower blood pressure.
            • Reduces the risk of death in people with heart failure.
            Coming soonComing soon
            Downsides and risks
            AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
            • Many possible side effects, especially when higher doses are used.
            • Can increase the risk of tumor growth.
            • Needs blood tests to monitor electrolytes and kidney function.
            • Can make you urinate more often.
            • Can make you sensitive to sunlight.
            • Shouldn't take it if you have a sulfa allergy.
            Coming soon
            • Makes you urinate more often.
            • Doesn't work well in people with severe kidney problems.
            Coming soon
            • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
            • Has many possible side effects, especially when higher doses are used.
            • Can increase the risk of tumor growth.
            • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
            Coming soonComing soon
            Tips from our pharmacists for people taking the medication
            AldactazideAmilorideHydrochlorothiazideDyazidespironolactoneTriamtereneInspra
            • Makes you urinate more often, so don't take it at bedtime.
            • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how it affects you.
            • Don't use supplements or salt substitutes that are high in potassium.
            • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
            • Tell your doctor about any dizziness, muscle weakness, skin changes, red or black tarry stool.
            • Can make your skin more sensitive to sun, so use proper protections.
            Coming soon
            • Starts working in about 2 hours.
            • Makes you urinate more often, so avoid taking it at bedtime.
            • Can cause dizziness in the first few days.
            • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
            • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
            • Requires routine blood tests to check kidney function.
            Coming soon
            • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
            • Don't use supplements or salt substitutes that are high in potassium.
            • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
            • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
            • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
            Coming soonComing soon
            Learn more
            More about AldactazideSide effectsAlternativesFDA package insert
            Have you used Aldactazide (Spironolactone / Hydrochlorothiazide)?
            Worth itNot sureNot worth it
            More about AmilorideSide effectsFDA package insert
            Have you used Midamor (Amiloride)?
            Worth itNot sureNot worth it
            More about HydrochlorothiazideSide effectsReviews & ratingsFDA package insert
            Have you used Microzide (Hydrochlorothiazide (Hctz))?
            Worth itNot sureNot worth it
            More about DyazideSide effectsReviews & ratingsFDA package insert
            Have you used Dyazide (Hydrochlorothiazide / Triamterene)?
            Worth itNot sureNot worth it
            More about spironolactoneSide effectsFDA package insert
            Have you used Aldactone (spironolactone)?
            Worth itNot sureNot worth it
            More about TriamtereneSide effectsFDA package insert
            Have you used Dyrenium (Triamterene)?
            Worth itNot sureNot worth it
            More about InspraSide effectsReviews & ratingsFDA package insert
            Have you used Inspra (Eplerenone)?
            Worth itNot sureNot worth it