Prescription onlyLower-cost generic availableClass: Cardiovascular

Aldactazide Alternatives

(spironolactone / hydrochlorothiazide)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Aldactazide (spironolactone / hydrochlorothiazide) to alternatives

These medications are comparable to Aldactazide (spironolactone / hydrochlorothiazide) or used for similar purposes.

Aldactazide
(spironolactone / hydrochlorothiazide)

Midamor
(amiloride)

Microzide
(hydrochlorothiazide )

Dyazide
(hydrochlorothiazide / triamterene)

Aldactone
(spironolactone)

Dyrenium
(triamterene)

Inspra
(eplerenone)

Lowers blood pressure. Removes extra water from your body. Aldactazide (Spironolactone / Hydrochlorothiazide) removes excess fluid in your body and lowers your blood pressure, while helping keep your potassium levels safe.Coming soon.Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.Helps lower blood pressure and protect the heart in people with heart failure. Inspra (eplerenone) lowers blood pressure and can help remove fluid when it's used with other drugs. It reduces the risk of death in people with heart failure and is usually used when people can't take spironolactone.
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Coupons for Aldactazide
Best available price for 30 (25mg/25mg) tablets of aldactazide
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactazide (spironolactone / hydrochlorothiazide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Midamor (amiloride)?
Worth itNot sureNot worth it
Reviews for hydrochlorothiazide
47%
-47% worse vs. Aldactazide
31%
-31% worse vs. Aldactazide
16%
+16% better vs. Aldactazide
139 reviews
Have you used Microzide (hydrochlorothiazide )?
Worth itNot sureNot worth it

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Have you used Dyazide (hydrochlorothiazide / triamterene)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Dyrenium (triamterene)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Inspra (eplerenone)?
Worth itNot sureNot worth it
Side effects
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra

We haven’t found good data for Aldactazide side effects.

FDA side effect reports for Aldactazide »

We haven’t found good data for Amiloride side effects.

FDA side effect reports for Amiloride »

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »

We haven’t found good data for Dyazide side effects.

FDA side effect reports for Dyazide »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Triamterene side effects.

FDA side effect reports for Triamterene »
  • High potassium 1%
  • Abnormal renal function 1%
  • Dizziness 1%
  • Diarrhea 1%
  • Coughing 1%
  • Fatigue 1%
  • Flu-like symptoms 1%
More Inspra side effects »
How it works
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
Aldactazide (Spironolactone / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure with two diuretics (water pills), hydrochlorothiazide and spironolactone. They act on different parts of your kidney to get rid of extra fluids.Coming soon.Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Coming soon.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Inspra (eplerenone) is an aldosterone antagonist. It blocks aldosterone (a hormone) and helps your kidneys get rid of excess fluid in your body, which helps lower blood pressure.
Type of medication
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
Prescription onlyPrescription onlyPrescription onlyPrescription only
Available as
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
Used for
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
  • Congestive Heart Failure Hypertension
  • Edema Hypertension
  • Edema
Risk factors for serious side effects
AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
  • Medicine that affects electrolytes
Detailed Aldactazide (spironolactone / hydrochlorothiazide) risks & warnings »
    Coming soon.
    • Current electrolyte imbalance
    • Lower kidney function
    • Dehydration
    • History of sulfa allergies
    • History of gout
    Detailed Microzide (hydrochlorothiazide ) risks & warnings »
      Coming soon.
      • Taking with alcohol
      • Taking other medicines that lower your blood pressure
      • Current kidney problems
      • Taking other medicines that increase potassium
      • Use of salt substitutes
      Detailed Aldactone (spironolactone) risks & warnings »
        Coming soon.
        • Taking with alcohol
        • Taking other medicines that lower your blood pressure
        • Current kidney problems
        • Medicines that increase potassium
        • Use of salt substitutes
        Detailed Inspra (eplerenone) risks & warnings »
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Kidneys and liver
        AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
        • Needs blood tests to monitor electrolytes and kidney function.
        • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
        • Aldactazide (Spironolactone / Hydrochlorothiazide) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
        No kidneys and liver related info.
        • Requires routine blood tests to check kidney function.
        No kidneys and liver related info.
        • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
        No kidneys and liver related info.
        • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
        • Shouldn't be used by people with kidney or liver damage.
        • Inspra (eplerenone) shouldn't be used by people with bad kidneys since it can hurt your kidneys or cause worse side effects, such as high potassium levels. Your doctor will do frequent blood tests to monitor your kidney function and electrolytes while you're on this drug.
        Pain
        AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
        No pain related info.No pain related info.No pain related info.No pain related info.
        • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
        No pain related info.No pain related info.
        Upsides and benefits
        AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
        • Lowers the risk of heart attack and stroke.
        • Has a low risk of causing muscle problems due to low potassium levels in your blood.
        • Gets rid of extra fluids in your body.
        • Helpful for people who tend to have low potassium levels.
        Coming soon
        • Does a good job getting rid of extra fluids in your body by making you urinate more.
        • A first-choice blood pressure treatment. Works especially well for people of African descent.
        • Lowers the risk of heart attack and stroke.
        • Good option if you have high blood pressure and heart failure.
        • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
        • Can be good for patients with osteoporosis since it raises the body's level of calcium.
        Coming soon
        • Has a low risk of causing muscle problems from low potassium levels in your blood.
        • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
        • Can lower blood pressure.
        • Reduces the risk of death in people with heart failure.
        Coming soon
        • Lowers your blood pressure.
        • It can help remove fluid from your body when it's used with other drugs.
        • Reduces the risk of death in people with heart failure.
        • It can have fewer side effects than spironolactone.
        Downsides and risks
        AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
        • Many possible side effects, especially when higher doses are used.
        • Can increase the risk of tumor growth.
        • Needs blood tests to monitor electrolytes and kidney function.
        • Can make you urinate more often.
        • Can make you sensitive to sunlight.
        • Shouldn't take it if you have a sulfa allergy.
        Coming soon
        • Makes you urinate more often.
        • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
        • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
        • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
        Coming soon
        • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
        • Has many possible side effects, especially when higher doses are used.
        • Can increase the risk of tumor growth.
        • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
        Coming soon
        • Inspra (eplerenone) isn't a first choice medicine for lowering blood pressure or getting rid of fluid in the body. It's usually used in combination with other medicines.
        • It can make you feel dizzy for the first few days. Be careful driving until you know how it affects you.
        • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
        • It can be very expensive compared to spironolactone.
        Tips from our pharmacists for people taking the medication
        AldactazideAmiloridehydrochlorothiazideDyazidespironolactoneTriamtereneInspra
        • Makes you urinate more often, so don't take it at bedtime.
        • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how it affects you.
        • Don't use supplements or salt substitutes that are high in potassium.
        • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
        • Tell your doctor about any dizziness, muscle weakness, skin changes, red or black tarry stool.
        • Can make your skin more sensitive to sun, so use proper protections.
        Coming soon
        • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
        • It makes you urinate more often, so don't take it at bedtime.
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
        • Requires routine blood tests to check kidney function.
        Coming soon
        • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
        • Don't use supplements or salt substitutes that are high in potassium.
        • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
        • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
        • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
        Coming soon
        • Inspra (eplerenone) can make you feel dizzy the first few days you're taking it.
        • It can increase your potassium to dangerous levels, so don't use salt substitutes or other products that contain potassium.
        • Women may notice breast tenderness or swelling and irregular periods.
        • Shouldn't be used by people with kidney or liver damage.
        • Your doctor will check the amount of potassium in your blood while you're on this drug.
        Learn more
        More about AldactazideSide effectsAlternativesFDA package insert
        Have you used Aldactazide (spironolactone / hydrochlorothiazide)?
        Worth itNot sureNot worth it
        More about AmilorideSide effectsFDA package insert
        Have you used Midamor (amiloride)?
        Worth itNot sureNot worth it
        More about hydrochlorothiazideSide effectsReviews & ratingsFDA package insert
        Have you used Microzide (hydrochlorothiazide )?
        Worth itNot sureNot worth it
        More about DyazideSide effectsReviews & ratingsFDA package insert
        Have you used Dyazide (hydrochlorothiazide / triamterene)?
        Worth itNot sureNot worth it
        More about spironolactoneSide effectsFDA package insert
        Have you used Aldactone (spironolactone)?
        Worth itNot sureNot worth it
        More about TriamtereneSide effectsFDA package insert
        Have you used Dyrenium (triamterene)?
        Worth itNot sureNot worth it
        More about InspraSide effectsReviews & ratingsFDA package insert
        Have you used Inspra (eplerenone)?
        Worth itNot sureNot worth it