Prescription onlyLower-cost generic available



Prescription onlyLower-cost generic available
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Removes extra water from your body.

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Our bottom line

Aldactone (Spironolactone) is helpful when added to another diuretic to get rid of excess fluid in your body. Doesn't work well on its own.

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  • Has a low risk of causing muscle problems due to low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.


  • Not very good at getting rid of excess fluids on its own. Should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • Needs to have blood tests done to monitor electrolyte levels and kidney function.
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Side effect rates for Aldactone (Spironolactone)

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These are side effects of Aldactone (Spironolactone) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Aldactone (Spironolactone)

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  • Use of Aldactone (Spironolactone) in rats showed higher risk of tumor growth, so it should only be used for FDA-approved indications.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Aldactone (Spironolactone)

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Kidneys and liver
  • Needs to have blood tests done to monitor electrolyte levels and kidney function.
  • Aldactone (Spironolactone) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
  • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.