Prescription onlyLower-cost generic available

Aldactone Alternatives

(Spironolactone)

Prescription onlyLower-cost generic available
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Compare Aldactone (Spironolactone) to alternatives

These medications are comparable to Aldactone (Spironolactone) or used for similar purposes.

Aldactone
(Spironolactone)

Midamor
(Amiloride)

Dyrenium
(Triamterene)

Inspra
(Eplerenone)

Removes extra water from your body. Aldactone (Spironolactone) is helpful when added to another diuretic to get rid of excess fluid in your body. Doesn't work well on its own.Coming soon.Coming soon.Coming soon.
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Reviews & ratings
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Have you used Aldactone (Spironolactone)?
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Have you used Midamor (Amiloride)?
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Have you used Dyrenium (Triamterene)?
Worth itNot sureNot worth it

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Have you used Inspra (Eplerenone)?
Worth itNot sureNot worth it
Side effects
AldactoneAmilorideTriamtereneInspra

We haven’t found good data for Aldactone side effects.

FDA side effect reports for Aldactone »

We haven’t found good data for Amiloride side effects.

FDA side effect reports for Amiloride »

We haven’t found good data for Triamterene side effects.

FDA side effect reports for Triamterene »

We haven’t found good data for Inspra side effects.

FDA side effect reports for Inspra »
How it works
AldactoneAmilorideTriamtereneInspra
Aldactone (Spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Coming soon.Coming soon.
Type of medication
AldactoneAmilorideTriamtereneInspra
Antihypertensive
Diuretic
Prescription only
Coming soon.
Coming soon.
Coming soon.
Available as
AldactoneAmilorideTriamtereneInspra
  • Pill
  • Pill
  • Pill
  • Pill
Used for (click to learn more)
AldactoneAmilorideTriamtereneInspra
  • Congestive heart failure Hypertension
  • Edema
  • Heart failure - Myocardial infarction with complication Hypertension
Risk factors for serious side effects
AldactoneAmilorideTriamtereneInspra
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
      Detailed Aldactone (Spironolactone) risks & warnings »
      Coming soon.Coming soon.Coming soon.
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Kidneys and liver
      AldactoneAmilorideTriamtereneInspra
      • Needs to have blood tests done to monitor electrolyte levels and kidney function.
      • Aldactone (Spironolactone) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
      No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
      Pain
      AldactoneAmilorideTriamtereneInspra
      • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
      No pain related info.No pain related info.No pain related info.
      Upsides and benefits
      AldactoneAmilorideTriamtereneInspra
      • Has a low risk of causing muscle problems due to low potassium levels in your blood.
      • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
      • Can lower blood pressure.
      • Reduces the risk of death in people with heart failure.
      Coming soonComing soonComing soon
      Downsides and risks
      AldactoneAmilorideTriamtereneInspra
      • Not very good at getting rid of excess fluids on its own. Should be used with another drug to help get rid of excess fluids.
      • Has many possible side effects, especially when higher doses are used.
      • Can increase the risk of tumor growth.
      • Needs to have blood tests done to monitor electrolyte levels and kidney function.
      Coming soonComing soonComing soon
      Tips from our pharmacists for people taking the medication
      AldactoneAmilorideTriamtereneInspra
      • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
      • Don't use supplements or salt substitutes that are high in potassium.
      • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
      • Tell your doctor about any muscle weakness, skin changes, red or black tarry stool.
      • Can take 2 to 3 days to see full diuretic effects and 2 to 3 weeks to see blood pressure lowering effects.
      Coming soonComing soonComing soon
      Learn more
      More about AldactoneSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Aldactone (Spironolactone)?
      Worth itNot sureNot worth it
      More about AmilorideSide effectsFDA package insert
      Have you used Midamor (Amiloride)?
      Worth itNot sureNot worth it
      More about TriamtereneSide effectsFDA package insert
      Have you used Dyrenium (Triamterene)?
      Worth itNot sureNot worth it
      More about InspraSide effectsReviews & ratingsFDA package insert
      Have you used Inspra (Eplerenone)?
      Worth itNot sureNot worth it