Over-the-counterLower-cost generic available

Alka-Seltzer Original

(Aspirin / Citric Acid / Sodium Bicarbonate)

Over-the-counterLower-cost generic available
  • Chewable tablet
  • Effervescent tablet
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Relieves heartburn, headache, and body pains.

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Our bottom line

Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) gives quick relief for headache, body pains, and upset tummies, but might be hard to swallow if you don't like the taste or fizz.

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Upsides

  • Works great if you have an upset stomach and a headache or body pain at the same time.
  • Works really fast.
  • Available over the counter without a prescription.
  • Cheap.
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1053 reviews

Downsides

  • Doesn't last very long.
  • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
  • Because it has aspirin in it, it increases the risk of bleeding, especially if you take any other blood thinning medicine.
  • Can't be used by people with allergy to aspirin.
  • You may not like the taste or fizz.
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Side effect rates for Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)

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These are side effects of Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)

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  • There are many different over the counter medications with the brand name Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate). Each one may contain different active ingredients. Be sure to read the labels carefully to understand what kind of medicine you have and what the correct dose should be.

Common concerns from people taking Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)

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Pregnancy
Food
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
  • If you have kidney or hyperparathyroid disease Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) can build up in your blood. This may can cause toxic levels of sodium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate); a different antacid would be better for you.