Over-the-counterClass: Respiratory

Alka-Seltzer Plus Cold And Cough

(aspirin / chlorpheniramine / dextromethorphan / phenylephrine)

Over-the-counterClass: Respiratory
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Relieves coughing and cold symptoms.

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Our bottom line

Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine) is good for multiple cold symptoms, but it's more medicine than you need if you only have one symptom.

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Upsides

  • Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • Phenylephrine (the decongestant ingredient) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Dextromethorphan (the cough suppressant ingredient) works well and has very few side effects.

Downsides

  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The aspirin in Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine) interacts with many other drugs and health conditions.
How it works

Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine) is a combination medicine that treats cold and flu symptoms. Aspirin relieves pain and reduces fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.

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Side effect rates for Alka-Seltzer Plus Cold And Cough (aspirin / chlorpheniramine / dextromethorphan / phenylephrine)

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These are side effects of Alka-Seltzer Plus Cold And Cough (aspirin / chlorpheniramine / dextromethorphan / phenylephrine) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Alka-Seltzer Plus Cold And Cough (aspirin / chlorpheniramine / dextromethorphan / phenylephrine)

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    • Higher risk if:
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day

    Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine) contains aspirin, which can cause serious problems including inflammation, bleeding, and ulcers in the stomach or intestines. The longer you take Alka-Seltzer Plus Cold And Cough (Aspirin / Chlorpheniramine / Dextromethorphan / Phenylephrine), the higher the risk is. If you notice blood or a dark/black color in your stool, tell your doctor right away.

Common concerns from people taking Alka-Seltzer Plus Cold And Cough (aspirin / chlorpheniramine / dextromethorphan / phenylephrine)

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Pregnancy
Pain
  • I used the effervescent tablets for aches, a painful lung cough, and a sore throat and it knocked my cough right out. I feel a little sleepy but am able to be at work.