Prescription or OTCLower-cost generic available



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  • Dissolving tablet
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Treats allergy symptoms.

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Prescription or OTCLower-cost generic available

Our bottom line

Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.


  • Relieves allergy symptoms, like sneezing, runny nose, and itching.
  • Approved to be used in kids and adults age 6 months and older.
  • Won't make you feel drowsy like some antihistamine medicines.
  • Available over-the-counter without a prescription.
  • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
  • It's okay to take with most other medications since it has very few interactions.


  • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
  • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
  • The dose needs to be adjusted for people with kidney problems.

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What to expect when you take Allegra (Fexofenadine)

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Tips from our pharmacists
  • Starts working in 1 to 2 hours depending on what dosage form you're taking.
  • Works best when taken regularly, even before symptoms are expected to appear.
  • Can make you feel dizzy or sleepy, so you can take it at bedtime.
  • Follow age-specific dosing and don't take more than recommended.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
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Side effects for Allegra (Fexofenadine)

From clinical trials of Allegra / Seasonal allergies (15 mg)  ( 538)

  • VomitingVomiting12% for Allegra vs.9% for placebo
  • DiarrheaDiarrhea4% for Allegra vs.3% for placebo
  • Somnolence/fatigueSomnolence/fatigue3% for Allegra vs.0% for placebo
  • Runny noseRunny nose1% for Allegra vs.1% for placebo

Risks and Warnings for Allegra (Fexofenadine)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that make you less alert

    Allegra (Fexofenadine) can lowers your ability to focus, think, and react. Be careful and avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Allegra (Fexofenadine)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Kidneys and liver
  • Upsides and downsides from our pharmacists
  • The dose needs to be adjusted for people with kidney problems.
  • Upsides and downsides from our pharmacists
  • Won't make you feel drowsy like some antihistamine medicines.
  • For any allergies & running nose taking Allegra doesn't cause any drowsiness even in the day time.