Prescription onlyLower-cost generic availableClass: Musculoskeletal

Zyloprim 

(allopurinol)

Prescription onlyLower-cost generic availableClass: Musculoskeletal
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Lowers uric acid levels in blood, and prevents gout flare-ups.

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Our bottom line

Zyloprim (allopurinol) works well to prevent gout attacks and is cheaper than some alternatives, but it takes a few weeks to start working.

Price and discounts
Best available price for 30 (300mg) tablets of allopurinol

Upsides

  • Zyloprim (allopurinol) works well to lower uric acid in the body.
  • It is available as a generic medication.
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Downsides

  • Zyloprim (allopurinol) can raise the number of gout attacks in the first few weeks.
  • It can take 2 to 6 weeks to feel the full effects of Zyloprim (allopurinol).
  • Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
How it works

Zyloprim (allopurinol) is a xanthine oxidase inhibitor. It lowers uric acid levels in your blood, which can stop gout attacks and kidney stones.

What to expect when you take Zyloprim (allopurinol) for Gout

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Side effect rates for Zyloprim (allopurinol)

Risks and Warnings for Zyloprim (allopurinol)

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  • It is common for people to have more gout attacks the first few weeks they start taking Zyloprim (allopurinol). Talk to your doctor so they can prescribe other medicines to stop the attacks from happening.

Common concerns from people taking Zyloprim (allopurinol)

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Pregnancy
Food
  • Take with food or milk to prevent an upset stomach.
Kidneys and liver
  • Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
Sleep
  • Taking Zyloprim (allopurinol) can make you feel sleepy or dizzy, especially if you're taking other medicines that can also make you feel sleepy, or if you're taking recreational drugs or drinking too much alcohol. Avoid driving or doing other tasks that require concentration until you know how this medication affects you. Get up very slowly from a seated or lying down position.