Prescription onlyLower-cost generic availableClass: Women's health

Alora Alternatives

(estradiol patch)

Prescription onlyLower-cost generic availableClass: Women's health
Back to: Full Site Navigation

Compare Alora (estradiol patch) to alternatives

These medications are comparable to Alora (estradiol patch) or used for similar purposes.

Alora
(estradiol patch)

Premarin
(conjugated estrogens)

Activella
(estradiol / norethindrone)

Prempro
(conjugated estrogens / medroxyprogesterone acetate)

Provera
(medroxyprogesterone)

Evamist
(estradiol spray)

Premarin Vaginal Cream
(conjugated estrogens)

Estring
(estradiol vaginal ring)

Divigel
(estradiol gel)

Relieves hot flashes and vaginal dryness due to menopause and strengthens your bones. Alora (estradiol patch) treats symptoms from low estrogen, and it may have fewer side effects than oral estrogen pills.Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis. Premarin (Conjugated Estrogens) relieves menopausal symptoms and prevents bone loss. It's an oral hormone replacement, so it can have a lot of side effects, and it's important to think through the benefits and potential hassles of this drug before using it.Relieves menopause symptoms and lowers your risk of osteoporosis. Activella (Estradiol / Norethindrone) is effective at treating symptoms related to menopause and preventing bone loss. The estrogen/progestin combo is a good options for women with an intact uterus.Coming soon.Regulates your menstrual cycle and supplements estrogen treatments for menopause. Provera (Medroxyprogesterone) works well to regulate your menstrual cycle and stop irregular bleeding. It also protects the uterus from estrogen's harmful effects.Relieves hot flashes due to menopause. Evamist (Estradiol Spray) is easy to use, absorbs well into your skin without needing to rub it in, and is a good option if you don’t want to use estrogen pills or patches.Relieves vaginal dryness and pain due to menopause. Premarin Vaginal Cream (Conjugated Estrogens) works well for vaginal problems caused by menopause, and it has fewer side effects than estrogen pills.Relieves vaginal dryness due to menopause. Estring (Estradiol Vaginal Ring) is a vaginal ring that may be less of a hassle than estrogen pills, gels, patches, or vaginal creams, but comes with the same side effects.Relieves hot flashes due to menopause. Divigel (Estradiol Gel) comes in 3 different strengths. It uses lower doses of estrogen than other hormone replacements and is easy to use and apply.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Alora (estradiol patch)?
Worth itNot sureNot worth it
Reviews for Premarin
50%
Same vs. Alora
43%
+7% better vs. Alora
11%
-39% worse vs. Alora
154 reviews
Have you used Premarin (conjugated estrogens)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Activella (estradiol / norethindrone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Prempro (conjugated estrogens / medroxyprogesterone acetate)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Provera (medroxyprogesterone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Evamist (estradiol spray)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Premarin Vaginal Cream (conjugated estrogens)?
Worth itNot sureNot worth it
Reviews for Estring
63%
-13% worse vs. Alora
39%
+11% better vs. Alora
18%
-32% worse vs. Alora
Have you used Estring (estradiol vaginal ring)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Divigel (estradiol gel)?
Worth itNot sureNot worth it
Side effects
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
  • Breast pain 7%
  • Heartburn 8%
  • Stomach pain 3%
  • Weakness 3%
More Alora side effects »
  • Vaginal hemorrhage 13%
  • Abdominal pain 5%
  • Breast pain 3%
  • Flatulence 4%
  • Pain 1%
  • Leukorrhea 3%
  • Endometrial hyperplasia 5%
  • Vaginitis 5%
  • Insomnia 1%
More Premarin side effects »
  • Breast Pain 24%
  • Upper Respiratory Tract Infection 18%
  • Headache 16%
  • Sinusitis 7%
  • Insomnia 6%
  • Back Pain 6%
  • Post-Menopausal Bleeding 5%
  • Uterine Fibroid 5%
  • Infection Viral 4%
  • Moniliasis Genital 4%
More Estradiol Norethindrone side effects »

We haven’t found good data for Prempro side effects.

FDA side effect reports for Prempro »

We haven’t found good data for Provera side effects.

FDA side effect reports for Provera »
  • Headache 3%
  • Breast tenderness 4%
  • Nasopharyngitis (common cold) 3%
  • Nipple pain 2%
  • Back pain 1%
  • Nausea 1%
  • Arthralgia (joint pain) 3%
More Evamist side effects »
  • Any side effect 8%
  • Abdominal pain 5%
  • Back pain 2%
  • Vaginal hemorrhage 14%
  • Arthralgia 2%
  • Upper respiratory infection 1%
More Premarin Vaginal Cream side effects »
  • Headache 13%
  • Leukorrhea 7%
  • Back Pain 6%
  • Genital Moniliasis 6%
  • Upper Respiratory Tract Infection 5%
  • Vaginitis 5%
  • Vaginal Discomfort/Pain 5%
  • Sinusitis 4%
  • Asymptomatic Genital Bacterial Growth 4%
  • Abdominal Pain 4%
More Estring side effects »
  • Nasopharyngitis 2%
  • Upper Respiratory Tract Infection 4%
  • Metrorrhagia 2%
  • Breast Tenderness 1%
More Divigel side effects »
How it works
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
Alora (estradiol patch) replaces an estrogen hormone that your body loses during and after menopause. Higher levels of the hormone relieve symptoms of low estrogen, menopause, and prevent bone loss.Premarin (Conjugated Estrogens) is an oral medication that replaces estrogen hormones during and after menopause. Higher levels of estrogen lower menopause-related hot flashes, flushing, night sweats, vaginal problems, and bone loss.Activella (Estradiol / Norethindrone) contains two hormones that work to balance hormone changes in your body during and after menopause. Estradiol (an estrogen) reduces hot flashes and night sweats and prevents bone loss, but can also harm cells in the uterus after menopause. Norethindrone (a progestin) protects the uterus from damage.Coming soon.Provera (Medroxyprogesterone) contains medroxyprogesterone, a progesterone hormone that works to balance hormone changes in the body. In premenopausal women, it prevents thickening of the uterus lining and regulates your menstrual cycle. It's also added to hormone therapy to protect the uterus from the harmful effects of estrogen.Evamist (Estradiol Spray) replaces estrogen hormones in your vagina that your body loses during menopause. Estrogen helps relieve symptoms of menopause, such as hot flashes, night sweats, and vaginal problems.Premarin Vaginal Cream (Conjugated Estrogens) is a topical medication that replaces estrogen hormones in the vagina to rebuild vaginal tissue and make vaginal sex more comfortable.Estring (Estradiol Vaginal Ring) is a vaginal ring that replaces estrogen hormones in your vagina that your body loses during menopause. Estrogen helps rebuild and maintain vaginal tissue, relieving symptoms of vaginal dryness, soreness, irritation, and painful sex.Divigel (Estradiol Gel) replaces estrogen hormones in your vagina that your body loses during menopause. Estrogen helps relieve symptoms of menopause, such as hot flashes, night sweats, and vaginal problems.
Type of medication
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
  • Patch
  • Pill
  • Pill
  • Pill
  • Pill
  • Spray
  • Vaginal cream, gel, or ointment
  • Vaginal ring
  • Cream, gel, or ointment
Used for
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
  • Treats Hot Flashes Night Sweats And Flushing In Women In Menopause
  • Hot Flashes And Night Sweats
  • Hot Flashes And Night Sweats
  • Menopause Moderate To Severe Abnormal Vasomotor Function Menopause Moderate To Severe Vaginal Atrophy Moderate To Severe Vulvar Atrophy Postmenopausal Osteoporosis
  • Amenorrhea
  • Hot Flashes And Night Sweats
  • Vaginal Dryness And Inflammation
  • Vaginal Dryness And Inflammation
  • Hot Flashes And Night Sweats
Risk factors for serious side effects
AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
  • Using estrogen for more than one year
  • Personal or family history of breast cancer
  • Personal or family history of blood clots
  • Smoking
Detailed Alora (estradiol patch) risks & warnings »
  • Using estrogen for more than one year
  • Personal or family history of breast cancer
  • Duration of use
  • Personal or family history of blood clots
  • Obesity
Detailed Premarin (conjugated estrogens) risks & warnings »
  • Using estrogen for more than one year
  • Personal or family history of breast cancer
  • Duration of use
  • Personal or family history of blood clots
  • Obesity
Detailed Activella (estradiol / norethindrone) risks & warnings »
    Coming soon.
    • Personal or family history of breast cancer
    • Family history of ovarian cancer
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    Detailed Provera (medroxyprogesterone) risks & warnings »
    • Using estrogen for more than one year
    • Personal or family history of breast cancer
    • Duration of use
    • Personal or family history of blood clots
    • Obesity
    Detailed Evamist (estradiol spray) risks & warnings »
    • Using estrogen for more than one year
    • Personal or family history of breast cancer
    • Duration of use
    • Personal or family history of blood clots
    • Obesity
    Detailed Premarin Vaginal Cream (conjugated estrogens) risks & warnings »
    • Using estrogen for more than one year
    • Personal or family history of breast cancer
    • Duration of use
    • Personal or family history of blood clots
    • Obesity
    Detailed Estring (estradiol vaginal ring) risks & warnings »
    • Using estrogen for more than one year
    • Personal or family history of breast cancer
    • Duration of use
    • Personal or family history of blood clots
    • Obesity
    Detailed Divigel (estradiol gel) risks & warnings »
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Alcohol
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
    • The spray is alcohol-based and flammable, so you shouldn't smoke while applying it.
    No alcohol related info.No alcohol related info.
    • The gel is alcohol-based and flammable, so you shouldn't smoke while applying it.
    Pain
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    No pain related info.
    • Get emergency care if you notice swelling or pain in your lower legs, sudden shortness of breath, or an unexplained severe headache.
    No pain related info.No pain related info.No pain related info.No pain related info.
    • For painful sex, it can work better than over-the-counter vaginal lubricants because Premarin Vaginal Cream (Conjugated Estrogens) treats the cause of the problem (low estrogen levels), not just the symptoms (dryness).
    • If you have severe vaginal dryness, you might have pain, bleeding, or infections from repeatedly inserting the applicator.
    No pain related info.No pain related info.
    Weight
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Can cause nausea, dizziness, bloating and breast tenderness.
    • Activella (Estradiol / Norethindrone) is a mixture of estrogen and progestin. It could cause a higher risk of ovarian cancer, especially if you have a family history of it. Your doctor can help you weigh the risks versus the benefits of this medication.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    No weight related info.
    • Provera (Medroxyprogesterone) contains progestin. It could cause a higher risk of ovarian cancer, especially if you have a family history of it. Your doctor can help you weigh the risks versus the benefits of this medication.
    • Can cause headache, weight gain, breast tenderness, or changes in mood.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    No weight related info.No weight related info.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    Upsides and benefits
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    • Alora (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
    • The patch is good for people who don't want to or can't take daily pills.
    • Can be worn while swimming, bathing, and showering.
    • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
    • Lowers your risk of fractures by keeping your bones healthy.
    • Premarin (Conjugated Estrogens) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
    • Lowers your risk of fractures by keeping your bones healthy. Make sure you also take enough calcium and Vitamin D.
    • Improves mood, energy, and mental alertness for some people.
    • Does not expose your partner to estrogen during sexual acitivities like vaginal estrogen creams.
    • Can help relieve symptoms of prostate cancer or advanced breast cancer in some people.
    • Activella (Estradiol / Norethindrone) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
    • Good choice for women with intact uterus. The norethindrone (a progestin) protects against the risk of cancer in the uterus from estrogen treatment.
    • Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
    • Improves mood, energy, and mental alertness for some people.
    • Mimvey brand is less expensive than other estrogen/progestin combination medicines.
    Coming soon
    • Provera (Medroxyprogesterone) can be used to treat multiple hormone problems in women.
    • After menopause, taking estrogen raises your risk of uterine cancer. However, taking progesterone, like in Provera (Medroxyprogesterone), along with estrogen gives you the positive effects of estrogen, but also prevents it from damaging your uterus.
    • Women taking an estrogen/progestin combination medications have a lower risk of uterine cancer.
    • Evamist (Estradiol Spray) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness, low energy).
    • Dries faster than topical estrogen gels.
    • Good for people who don't want to take daily pills.
    • Fewer side effects than pills since lower amounts of estrogen are used in topical sprays.
    • Women in studies have seen the severity and number of hot flashes lower by half within 4 weeks of using Evamist (Estradiol Spray).
    • Very few women had skin irritation from the medicine.
    • Depending on your symptoms, your dose may change, but you can still use the same spray pump no matter what your dose is.
    • Can lower your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
    • Premarin Vaginal Cream (Conjugated Estrogens) relieves vaginal dryness and irritation to make sex more enjoyable.
    • Works locally in the vagina and doesn't expose the rest of your body to estrogen like pills do.
    • Premarin Vaginal Cream (Conjugated Estrogens) doesn't need to be used forever, so you can work with your doctor to see how long you’ll need to continue treatment.
    • For painful sex, it can work better than over-the-counter vaginal lubricants because Premarin Vaginal Cream (Conjugated Estrogens) treats the cause of the problem (low estrogen levels), not just the symptoms (dryness).
    • Estring (Estradiol Vaginal Ring) relieves vaginal dryness and irritation to make sex more enjoyable.
    • Works locally in the vagina and doesn't expose the rest of your body to estrogen like pills do.
    • Good option for people who don't want to take oral pills.
    • Generally works well with fewer side effects.
    • Many women think Estring (Estradiol Vaginal Ring) is easy to insert and comfortable to use.
    • In a 12-week study, Estring (Estradiol Vaginal Ring) worked well to improve vaginal problems, reduced pain during urination, and sudden urges to urinate.
    • Estring (Estradiol Vaginal Ring) slowly releases estrogen over the 90 days the ring is in place, so you only have to remove and insert a new one every three months.
    • Divigel (Estradiol Gel) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness).
    • Good for people who don't want to take daily pills.
    • The pre-measured packets are easy to use and can be taken anywhere.
    • Fewer side effects than pills since there are lower amounts of estrogen in topical gels.
    • In studies, when people used low doses of Divigel (Estradiol Gel), their symptoms started to improve in 5 weeks and they felt continued improvement over 8 to 12 weeks. People using the highest doses of Divigel (Estradiol Gel) felt better in just 2 weeks.
    • Divigel (Estradiol Gel) is available in 3 strengths.
    • Very few women (less than 1%) had skin irritation from the medicine.
    • Can lower your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
    • Improves mood, energy, and mental alertness for some people.
    Downsides and risks
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    • You need to replace Alora (estradiol patch) twice a week, compared to other patches that are once a week.
    • Patches can fall off.
    • Increases your risk of uterine and breast cancer.
    • Increases your risk of developing blood clots and stroke.
    • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
    • Can't be used in people with liver problems.
    • More potential side effects than estrogen creams since it exposes your whole body to estrogen.
    • Increases your risk of uterine and breast cancer.
    • If you have your uterus, you have to take Premarin (Conjugated Estrogens) with another hormone called progestin to lower your risk of uterine cancer.
    • Increases your risk of developing blood clots and stroke.
    • Can't be used in people with liver problems.
    • Can be expensive since it's only available as a brand name product.
    • More potential side effects since it exposes your whole body to two hormones, estrogen and norethindrone (a progestin).
    • Increases your risk of developing blood clots and stroke.
    • You may get irregular bleeding and spotting that can last a few months to a year.
    Coming soon
    • You can't take Provera (Medroxyprogesterone) if you've had a hysterectomy (your uterus removed). You also can't take it if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, certain kinds of cancer, stroke, heart attack, liver problems, or bleeding problems.
    • Increases your risk of endometrial and breast cancer.
    • If you have your uterus, you have to use Evamist (Estradiol Spray) with another hormone called progestin to lower your risk of uterine cancer.
    • Increases your risk of developing blood clots and stroke.
    • Can't be used in people with liver problems.
    • It's possible to expose other people to the estrogen before it's absorbed by your skin.
    • Can be expensive since it's only available as a brand name product.
    • Vaginal estrogens can weaken latex (rubber) condoms, cervical caps, and diaphragms, so you can't rely on these for birth control for 72 hours after using Premarin Vaginal Cream (Conjugated Estrogens).
    • If you have severe vaginal dryness, you might have pain, bleeding, or infections from repeatedly inserting the applicator.
    • Some of the medicine can be absorbed into your partner's skin, so you can’t have vaginal sex right after using Premarin Vaginal Cream (Conjugated Estrogens).
    • Even though Premarin Vaginal Cream (Conjugated Estrogens) is used in the vagina, it's possible some of the estrogens will get into the rest of your body and cause side effects that happen more often with estrogen pills.
    • Estring (Estradiol Vaginal Ring) may not be the best estrogen product if you have a narrow vagina or frequent vaginal infections.
    • The ring can fall out without you noticing it.
    • Increases your risk of endometrial (uterine cancer).
    • If you have your uterus, you might need to use Estring (Estradiol Vaginal Ring) with another hormone called progestin to lower your risk of uterine cancer.
    • Can be expensive since it's only available as a brand name product.
    • Increases your risk of endometrial and breast cancer.
    • If you have your uterus, you have to use Divigel (Estradiol Gel) with another hormone called progestin to lower your risk of uterine cancer.
    • Increases your risk of developing blood clots and stroke.
    • Can't be used in people with liver problems.
    • It's possible to expose other people to the estrogen before it's absorbed by your skin.
    • Can be expensive since it's only available as a brand name product.
    Tips from our pharmacists for people taking the medication
    AloraPremarinEstradiol NorethindronePremproProveraEvamistPremarin Vaginal CreamEstringDivigel
    • Remove the patch by tearing the package by hand and not with scissors. Never cut the patch.
    • Apply the sticky side of the patch to clean, dry, hairless skin below your belly button on areas as instructed by the manufacturer (never on your breast).
    • Replace the patch twice a week (every 3-4 days) on a different area of the skin to lower the risk of skin irritation.
    • Fold together the sticky sides of used patches before throwing them away to prevent exposing others to the medicine. Don't flush them down the toilet.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Tell your doctor about any unusual vaginal bleeding.
    • Take Premarin (Conjugated Estrogens) at the same time each day. If you miss a dose, take it as soon as possible, but if it’s almost time for your next dose, take only that dose.
    • Use the lowest dose possible of Premarin (Conjugated Estrogens) and take it only as long as needed. Talk to your doctor regularly to see if you still need treatment. If you’re taking Premarin (Conjugated Estrogens) only for vaginal symptoms or to prevent bone loss, there are other medicines that can work better with fewer side effects (like a vaginal cream for menopause symptoms, or non-estrogen medicine for bone loss).
    • Can cause nausea, dizziness, bloating and breast tenderness.
    • Get emergency care if you notice swelling or pain in your lower legs, sudden shortness of breath, or an unexplained severe headache.
    • Tell your doctor about any unusual vaginal bleeding.
    • Shouldn't be used forever. Talk to your doctor regularly to see if you still need treatment.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Tell your doctor about any unusual vaginal bleeding.
    • Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
    Coming soon
    • The dose of Provera (Medroxyprogesterone) will be different depending on what you’re using it for, so take it exactly the way your doctor tells you.
    • Talk to your doctor every few months about using the lowest possible dose of Provera (Medroxyprogesterone). Since there can be a lot of long-term side effects, take it only as long as you need it.
    • Can cause headache, weight gain, breast tenderness, or changes in mood.
    • If you're taking Provera (Medroxyprogesterone) to regulate your period, you'll get withdrawal bleeding 3 to 7 days after stopping Provera (Medroxyprogesterone).
    • Spray with the container upright and the cone flat against your skin on the inside of your forearm. If more than one spray is needed, always use a different area on your forearm.
    • Don't put it on your face, breasts, vagina, or irritated skin.
    • Don't rub it in. Let the spray dry for about 2 minutes before dressing, and don't get the application site wet for at least 1 hour.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Tell your doctor about any unusual vaginal bleeding.
    • Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
    • The spray is alcohol-based and flammable, so you shouldn't smoke while applying it.
    • Your doctor will tell you how often to use Premarin Vaginal Cream (Conjugated Estrogens). If you're taking Premarin Vaginal Cream (Conjugated Estrogens) regularly, use it around the same time each day.
    • Attach the applicator to the tube. Once the dose is measured, insert the applicator deeply into your vagina, and press the plunger to release all the medicine. Clean the applicator after each use.
    • More effective if you use it at bedtime.
    • Consider wearing a panty liner after use.
    • Most people don't have many side effects, but temporary nausea, dizziness, bloating, and breast tenderness are possible.
    • Insert the ring as deeply as possible into your vagina. You shouldn't feel the ring once it's inserted.
    • The ring is good for 90 days in your vagina. If it falls out before the 90 days are up, just clean it with warm water and reinsert.
    • You don’t have to remove Estring (Estradiol Vaginal Ring) to treat a vaginal infection or have sex.
    • It can take up to 2 to 3 weeks to feel the full benefits.
    • Most people don't have many side effects, but temporary nausea, dizziness, bloating, and breast tenderness are possible.
    • Tell your doctor about any unusual vaginal bleeding.
    • Apply all of the gel in the packet to dry, clean, unbroken skin on the right or left upper thigh, alternating each day.
    • Don't put it on your face, breasts, vagina, or irritated skin.
    • Don't rub it in. Let the gel dry before dressing, and don't wash the application site for at least an hour.
    • Wash your hands well after applying the gel.
    • The gel is alcohol-based and flammable, so you shouldn't smoke while applying it.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Tell your doctor about any unusual vaginal bleeding.
    • Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
    Learn more
    More about AloraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Alora (estradiol patch)?
    Worth itNot sureNot worth it
    More about PremarinSide effectsReviews & ratingsFDA package insert
    Have you used Premarin (conjugated estrogens)?
    Worth itNot sureNot worth it
    More about Estradiol NorethindroneSide effectsReviews & ratingsFDA package insert
    Have you used Activella (estradiol / norethindrone)?
    Worth itNot sureNot worth it
    More about PremproSide effectsReviews & ratingsFDA package insert
    Have you used Prempro (conjugated estrogens / medroxyprogesterone acetate)?
    Worth itNot sureNot worth it
    More about ProveraSide effectsReviews & ratingsFDA package insert
    Have you used Provera (medroxyprogesterone)?
    Worth itNot sureNot worth it
    More about EvamistSide effectsReviews & ratingsFDA package insert
    Have you used Evamist (estradiol spray)?
    Worth itNot sureNot worth it
    More about Premarin Vaginal CreamSide effectsReviews & ratingsFDA package insert
    Have you used Premarin Vaginal Cream (conjugated estrogens)?
    Worth itNot sureNot worth it
    More about EstringSide effectsReviews & ratingsFDA package insert
    Have you used Estring (estradiol vaginal ring)?
    Worth itNot sureNot worth it
    More about DivigelSide effectsReviews & ratingsFDA package insert
    Have you used Divigel (estradiol gel)?
    Worth itNot sureNot worth it